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EN
Two strains (TK-900/4a and NIA-3) of Aujeszky’s disease virus as well as two strains (McIntyre and HSZP) and two clinical isolates of herpes simplex virus type 1 were found to agglutinate C57B110/su mouse red blood cells. This haemagglutination was inhibited by antisera that neutralize viral infectivity.
EN
In calves at the age of 2—3 months experimentally infected with BHV-1 clinical signs, humoral and cellular responses and the intensity of delayed skin hipersensitivity were examined. The examinations were performed from 3 to 56 day post infection, e.g. at early period of infection. It was found that apart from typical clinical signs and humoral response to BHV-1 infection, cellular immune response measured by the test of blastic transformation of leukocytes appeared by about 7 days before humoral immune response and that it persists only up to the day 21 post infection. In the leukocyte migration tests, leukocyte inhibition was noted at the day 7 and from that day since the end of observation acceleration of leukocyte migration was noted. A delayed skin hipersensitivity measured by allergic skin test appeared between day 21 and 28 post infection.
EN
In piglets of the miniature pig there was assessed the influence of Levamisole or Biotropin on the humoral and cellular immune response against Aujeszky’s disease virus and on some nonspecific indices of immunity. It was found that the drugs did not influence humoral response, i.e. they did not increase the level of antibodies; however, they enhanced specific cellular response. In animals treated with the drugs there were observed an increase of migration inhibition of leukocytes and the augmented index of lymphocyte transformation. Besides, a higher concentration of lysozyme and the activity of phagocytes were noted.
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