Wyniki wyszukiwania - Biblioteka Nauki

1

Leukemic stem cells: from metabolic pathways and signaling to a new concept of drug resistance targeting

100%

Styczynski J. , Drewa T.

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tom 54

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nr 4

717-726

EN

Cancer stem cells are a small subset of cancer cells constituting a reservoir of self-sustaining cells with the exclusive ability to self-renew and maintain the tumor. These cells are identified by specific stem cell markers: antigens, molecules and signaling pathways. Transcription factors and molecules associated with oncogenesis, such as NF-κB, Bmi-1, Notch, WNT beta-catenin, Sonic hedgehog and their biochemical pathways, active only in a small minority of cancer cells might play key roles in determining the biology and the overall long-term behavior of a tumor. The molecules and pathways specific for cancer stem cells, which contribute to their drug resistance, are potential targets for new therapeutic strategies.

2

Zaburzenia kontroli fazy G1 cyklu komorkowego podczas onkogenezy.

80%

Czajkowski R. , Drewa T. , Olszewska D. , Wozniak A.

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2000

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tom 46

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nr 4

309-317

3

Badania wstepne nad zastosowaniem alginianu do przeszczepiania chondrocytow w sciane pecherza moczowego szczura

61%

Drewa T. , Wolski Z. , Galazka P. , Sir J. , Wozniak A. , Czaplewski A.

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nr 3

213-224

4

Regeneracja tkanki chrzęstnej szczura z użyciem żelu kolagenowego i mezenchymalnych komórek macierzystych szpiku kostnego, wstępne badania in vivo

61%

Bajek A. , Skopińska-Wiśniewska J. , Rynkiewicz A. , Jundziłł A. , Nowacki M. , Drewa T.

Engineering of Biomaterials

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2013

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tom Vol. 16, no. 122-123 spec. iss.

49--50

5

Biomateriały na bazie kolagenu i hydrolizatów elastyny modyfikowane promieniowaniem UV

61%

Skopińska-Wiśniewska J. , Sionkowska A. , Joachimiak R. , Kaźnica A. , Drewa T. , Bajer K. , Dzwonkowski J.

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tom Vol. 10, no. 69-72

67-69

6

Adipose-derived stem cells as a tool in cell-based therapies

61%

Bajek A. , Gurtowska N. , Olkowska J. , Kazmierski L. , Maj M. , Drewa T.

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2016

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tom 64

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nr 6

7

The expression of p63 and Ck HMW in magnum and infundibulum of Gallus domesticus oviduct

51%

Stadnicka K. , Marszalek A. , Kozlowska I. , Walasik K. , Bodnar M. , Bajek A. , Porowinska D. , Drewa T. , Bednarczyk M.

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2014

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tom 62

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nr 3

8

Efficient source of cells in proximal oviduct for testing non-viral expression constructs in the chicken bioreactor model and for other in vitro studies

51%

Stadnicka K. , Bodnar M. , Marszalek A. , Bajek A. , Drewa T. , Plucienniczak G. , Chojnacka-Puchta L. , Cecuda-Adamczewska V. , Dunislawska A. , Bednarczyk M.

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nr 1

9

The effect of brachytherapy on antioxidant status and lipid peroxidation in patients with cancer of the uterine cervix

51%

Mila-Kierzenkowska C. , Kedziora-Kornatowska K. , Wozniak A. , Drewa T. , Wozniak B. , Drewa S. , Krzyzanska-Malinowska E. , Makarewicz R.

Cellular and Molecular Biology Letters

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2004

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tom 09

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nr 3

EN

The aim of this study was to investigate the effect of brachytherapy on lipid peroxidation and antioxidant status in patients with uterine cervix cancer. The study was conducted on 84 uterine cervix cancer patients from the Brachytherapy Department of the Regional Centre of Oncology in Bydgoszcz. Patients with uterine cervix cancer were found to have elevated levels of lipid peroxidation and antioxidant defence system impairment relative to healthy females. The results of the study indicate that brachytherapy has no direct effect on the antioxidant system of patients with uterine cervical carcinoma. However, the normalisation of catalase and glutathione peroxidase activity and erythrocyte TBARS level observed six months after the end of therapy may be due to the arrest of the progression of the disease.

10

Transdifferentiation of bone marrow mesenchymal stem cells into the islet-like cells: the role of extracellular matrix proteins

36%

Pokrywczynska M. , Lewandowska M. A. , Krzyzanowska S. , Jundzill A. , Rasmus M. , Warda K. , Gagat M. , Deptula A. , Helmin-Basa A. , Holysz M. , Nowacki M. , Buchholz L. , Bodnar M. , Marszalek A. , Grzanka A. , Jozwicki W. , Michalkiewicz J. , Drewa T.

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nr 5