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Drobnoustroje zyjace w nietypowych warunkach

100%

Niedzwiedzka P. , Deptula W.

tom 108

nr 07-09

225-227

Fagocytoza granulocytow obojetnochlonnych - fakty znane i nieznane

100%

Niedzwiedzka P. , Deptula W.

tom 64

nr 06

749-752

The paper concerns a very important element of innate immunity, i.e. the polimorfonuclear cell, which by the process of phagocytosis participates in defending the macroorganism against pathogens. New facts about phagocytosis have been described - metalloproteises and galectins regulating migration, selectins enhancing adherence, opsonins taking part in absorbance and oxygen dependent and independent systems as mechanisms of intracellular digestion and killing. Moreover, fate of the phagocyted polimorfonuclear cell has been shown, including apoptosis.

Produkty mleczne a odporność

100%

Niedzwiedzka P. , Deptula W.

2006

tom 33

nr 4

309-317

Receptory TLR w zarazeniach pierwotniakami

80%

Sliwa J. , Niedzwiedzka P. , Tokarz-Deptula B. , Deptula W.

tom 64

nr 09

1098-1103

Parasite diseases constitute a tremendous danger for human life all over the world, hence there is an urgent need for the recognition of the defense mechanisms of our body against these protozoan pathogens. The aim of this review has been to present the role of Toll-like receptors (TLRs) as constituents of innate immunity engaged in the fight against parasites, mainly protozoan, that are the cause of illness among people and animals. This review also shows the means by which the protozoan can control the immunological response to extend their survival inside the host.

Rola i znaczenie receptorow Toll-podobnych w odpornosci

80%

Deptula W. , Tokarz-Deptula B. , Niedzwiedzka P.

2006

tom 45

nr 3

221-231

Wskazniki odpornosci u krolikow eksperymentalnie zakazonych szczepami wirusa RHD o odmiennych wlasciwosciach hemaglutynacyjnych

80%

Tokarz-Deptula B. , Niedzwiedzka P. , Hukowska-Szematowicz B. , Deptula W.

nr 10

1251-1254

The aim of the study was to monitor alterations in selected indices of innate immunity (the phagocytic index and percent of phagocytes) and acquired immunity (numbers of lymphocytes T and their Th and Tc/Ts subpopulations) in 60 rabbits experimentally infected with haemagglutinogenic Czech strain CAMP V-351 and non-haemagglutinating Polish BLA. The haemagglutinogenic Czech strain CAMP V-351 is active only in select indices of innate immunity, whereas non-haemagglutinating Polish strain BLA is reactive in the parameters of acquired immunity. Therefore, the obtained results permit the conclusion that the examined strains are not only serologically different but they also induce distinct patterns of immune responses, which provides evidence of immunotypes among this virus.

Znaczenie receptorow Toll-podobnych u zwierzat gospodarskich

80%

Niedzwiedzka P. , Tokarz-Deptula B. , Deptula W.

nr 08

900-903

Research on Toll-like receptors (TLR), an important receptor family in immunology, has recently been extended to research connected with animals, such as ruminates (sheep and cattle), swine, dogs, cats and poultry. In ruminates TLR1, 2, 3, 4, 5, 6, 7, 8, 9 and 10 have been demonstrated; in swine, TLR2, 4, 6 and 9; in dogs,TLR2, 4 and 9; in cats TLR1, 2, 3, 4, 5, 6, 7, 8 and 9; whereas in poultry TLR1, 2, 3, 4, 5, 6 and 10 have been noted. On the basis of the homology between TLR in animals and in human and mice and the role and place of occurrence it has been proved that TLR plays a very important role in animals, similar to that in humans and mice.