In this paper we show some interpretation of the genetic code design. We proceed from the discovery of DNA structure to current stage of the molecular biology. Generally we introduce the basic semiotic assumptions of molecular biology in the description of the structure of DNA, proteins and genetic code. We focus on interpretations of Francis Crick, another molecular biologists, biosemioticians and linguists. For the aims of the paper we describe some fundaments of molecular biology. Core of our text is quantitative analysis (n-gram structure, Zipf ’s law) of mRNA strings and natural language text. We take into consideration representative quantitative analysis of DNA, RNA and proteins too. Our analysis of mRNA confirms the assumption that the design of the genetic code cannot analogize DNA bases and letters.
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