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Levels of antioxidant substances, acute phase response and lipid peroxidation in the left and right abomasum displacement in cows

100%

Mamak N. , Devrim A. K. , Aksit H. , Aytekin I. , Yildiz R.

2013

tom 16

nr 4

The aim of the present study was to assess metabolic changes occurring in Holstein cows with left or right abomasal displacement. Total sialic acid (TSA) values of the left abomasal displacement (LDA) group were elevated significantly (p<0.0001) as compared to the controls. In the LDA group, serum ceruloplasmin (CPN) and aspartate transaminase (AST) levels were increased significantly (p<0.0001) as well. Compared to the control group, serum glutathione (GSH) level was decreased significantly in both LDA and right abomasal displacement (RDA) groups (p<0.0001). Among the clinical examination parameters, rumen contraction rates were decreased in both LDA and RDA groups significantly (p<0.0001). These results suggest that inflammatory and oxidative parameters might have taken part in the pathogenesis of abomasal displacement. In this regard, anti-cytokine and anti-oxidant therapies developed in human medicine may also play a potential therapeutic role in the fatty liver and abomasal displacement in cattle.

Trace elements and biochemical and haematological parameters in cows with Downer syndrome

86%

Onmaz A. , Aytekin I. , Aypak S. U. , Gunes V. , Kucuk O. , Ozturk A. S.

Bulletin of the Veterinary Institute in Puławy

2011

tom 55

nr 3

The objective of this study was to investigate the serum concentrations of iron, manganese, cobalt, copper, zinc, and copper/zinc ratio in Downer cows. The study was performed on 20 recumbent Downer cows and 20 healthy cows. The serum concentrations of iron (P=0.002) and copper (P=0.035) were lower in Downer cows compared with the healthy cows. Serum zinc concentrations, although not significantly (P=0.162), were also lower in Downer cows compared with the healthy cows. Cows with Downer syndrome had greater concentrations of serum AST (P<0.001), LDH (P=0.003), and CK (P<0.001). Other biochemical parameters remained unchanged. RBC (P=0.026), Hb (P=0.029), and MCV (P<0.001) in cows with Downer syndrome had lower values compared with those of healthy ones. However, WBC in cows with Downer syndrome had greater values (P<0.00l) compared with those of healthy ones. Other haematological parameters remained similar between Downer cows and healthy cows. It was concluded that serum iron and copper concentrations may play an important role for the aetiology and/or pathogenesis of Downer cows. These elements may be supplemented for the prevention and therapy of recumbency in cows.

Levels of antioxidant substances, acute phase response and lipid peroxidation in the left and right abomasum displacement in cows

86%

Mamak N. , Devrim A. K. , Aksit H. , Aytekin I. , Yıldız R.