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Monitoring of selected immunological parameters in bitches with glandular cystic hyperplasia - pyometra complex before and after ovariohysterectomy

100%

Mojzisova J. , Valocky I. , Maracek I.

2000

tom 03

nr 1

The aim of the study was to determine the degree of phagocytic activity of neutrophils, lymphocyte histogenesis and total immunoglobulin level in six bitches with glandular cystic hyperplasia - pyometra complex (GCH - PC) before and after ovariohysterectomy in comparison to healthy dogs. Haematological study showed significant increases (P<0.005) in the white blood cell count and neutrophilia. After ovariohysterectomy these parameters gradually returned to normal. The phagocytic ability (expressed as phagocytic activity PA and index of phagocytic activity IPA) of neutrophils was impaired in bitches wit GCH - PC and has improved during the therapy. The degree of concanavalin A induced lymphocyte blastogenesis expressed as a stimulation index was significantly (P<0.005) depressed in affected bitches and after surgical treatment had not reached values comparable with that found in healthy dogs. The level of total immunoglobulins was significantly (P<0.05) decreased at the beginning of observation and gradually increased after treatment. The results of the present study have provided usuful information for diagnosis and prognosis of GCH - PC in bitches because the success of the treatment and recovery from the GCH - PC is in direct relation with the optimal condition of the immune system.

Factors influencing serum concentrations of total thyroxine, free thyroxine and thyrotropin in healthy dogs of various breeds

88%

Fialkovicova M. , Benkova M. , Mardzinova S. , Mojzisova J. , Goldirova K.

nr 08

The aim of this article is to obtain the correct specification of reference ranges of TT4, fT4 and cTSH with regard to the influence of physiological factors on thyroid gland functioning, including breed size, age and season. The reference range for TT4 was divided according to the size of the dog breeds. In large breeds, over 27 kg of live weight, it should be represented by the interval TT4 = 17-43 nmol/l; in medium size breeds, from 12 to 27 kg of live weight, it should be TT4 = 23-50 nmol/l and in small breeds, up to 12 kg of live weight, the reference range should move within TT4 = 27-55 nmol/l. The reference range of free thyroxin does not depend on the size of the breed and it is represented by a uniform standard: fT4 = 10-22 pmol/l. The reference level for cTSH in healthy dogs should not exceed cTSH = 0-0.35 ng/ml.

Immune response and immunomodulatory effect of levamisole in immunosuppressed dogs vaccinated against parvovirosis

88%

Mojzisova J. , Hromada R. , Paulik S. , Ondrasovic M. , Bajova V.

nr 2

Dog’s genotype of Giardia duodenalis in human: first evidence in Europe

76%

Strkolcova G. , Madar M. , Hinney B. , Goldova M. , Mojzisova J. , Halanova M.

nr 4