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EN
The relationship between gastrin levels and presence of Helicobacter-like organisms (HLO) in dogs with acute or chronic gastritis was investigated. For this purpose, a total of 52 crossbred Kangal Dogs aging 2-5 years were used; including 12 dogs with acute gastritis, 25 dogs with chronic gastritis, and 15 healthy dogs. Blood samples were collected from the vena cephalica. Serum gastrin levels were measured using commercial competitive binding radioimmunoassay. HLO were found in 64%, 58.3%, and 60% of animals with chronic gastritis or acute gastritis, and controls, respectively. The gastrin levels in dogs with chronic gastritis were higher than in those with acute gastritis and controls. There were no significant differences between the gastrin levels in all groups, with regard to HLO positive versus HLO negative dogs. In conclusion, HLO incidence was generally found in high levels in all the dogs. However, HLO did not primarily affect the stomach mucosal damage. In the mean time, there was no relation between the levels of serum gastrin in dogs with gastritis, either being HLO positive or negative. The results of the study showed that higher gastrin levels in dogs with gastritis were related to severe gastric lesions and mucosal damage.
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EN
The aim of the study was to investigate acid-base changes and to determine some serum biochemical parameters in dehydrated calves with diarrhoea according to the degree of dehydratation. Thirty diarrhoeic dehydrated calves submitted to treatment in the university clinic, were used in the study. The calves were accessed as suitable for this study, if they were moderately or severely dehydrated according to clinical symptoms. All sick calves had the usual yellow and watery diarrhoea. Calves with 4% to 8% dehydration (moderate) had a weak suckle reflex, dry mucous membranes, warm mouth and partly good muscular tone. Calves with 10% and above dehydration (severe) were unable to stand, and had no suckling reflex and cold mouth. The mean pH, base excess, chloride (only severely dehydrated group) and sodium were -significantly decreased in both moderately and severely dehydrated groups. On the other hand, potassium, phosphorus, HCO₃⁻ and anion gap levels were increased, compared to that of the control group. Results of this study showed that there was a relationship between the base excess and anion gap, with a degree of clinical dehydration. However, there may not be an exact correlation between the degree of dehydration and the severity of acidosis. Based on the clinical symptoms, the results of this study could be a useful tool under field conditions, in estimating the base excess in diarrhoeic dehydrated calves, when acidosis therapy is needed.
EN
The changes in some biochemical and haematological parameters in three cows with post-parturient haemoglobinuria were described. The animals were 4, 6, and 7 years of age. These cows had calved in the autumn. Post-parturient haemoglobinuria in the cattle occurred at a post-partum of about 3 weeks. The cows received phosphorus supplementation and supportive treatment. The mean serum phosphorus level in the affected cows was significantly lower compared with healthy cows. In the meantime, the blood RBC, PCV, MCHC, and Hb values were also significantly lower compared with healthy cows. In conclusion, the deficiency of phosphorus could be responsible for the development of post-parturient haemoglobinuria in the cows.
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