Wyniki wyszukiwania - Biblioteka Nauki

Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

Ograniczanie wyników

Znaleziono wyników: 4

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Digital image analysis and visualization of early caries changes in human teeth

100%

Kaczmarek E. , Surdacka A. , Matthews-Brzozowska T. , Miśkowiak B.

tom Vol. 23, No. 2

551--558

The primary aims were the visualization, digital image analysis and X-ray EDS microanalysis to evaluate caries lesions in human premolars, with and without resin sealants, and light and scanning electron microscopic observations of hard dental tissues before and after the use of experimental protective strontium-fluoride toothpaste. The material consisted of healthy premolars extracted for orthodontic reasons, sectioned into slices. Sections of tooth crowns were digitized with a light microscope. The area of enamel demineralization was then measured. The in situ model was developed by placing the samples on the buccal surfaces of the first molars in healthy subjects, and exposing them to the use of the experimental toothpaste for 3 or 6 months. X-ray EDS microanalysis was undertaken to examine the Ca and Sr content on the enamel surface and at 15, 30, 60 and 100 microns depth. The results showed that the toothpaste induces an increased deposition of Ca in sub-superficial layers of the damaged enamel. The role of digital imaging needs to be defined with the diagnostic problem of the patient to plan an effective prophylaxis and treatment of early caries.

Assessment of the pathway of apoptosis involving PAR-4, DAXX and ZIPK proteins in CLL patients and its relationship with the principal prognostic factors

63%

Bojarska-Junak A. , Sieklucka M. , Hus I. , Wasik-Szczepanek E. , Kusz M. L. , Surdacka A. , Chocholska S. , Dmoszynska A. , Rolinski J.

tom 49

nr 1

Analysis of immunohistochemical expression of proinflammatory cytokines (IL-1alfa, IL-6, and TNF-alfa) in gallbladder mucosa: comparative study in acute and chronic calculous cholecystitis

63%

Kasprzak A. , Szmyt M. , Malkowski W. , Przybyszewska W. , Helak-Lapaj C. , Seraszek-Jaros A. , Surdacka A. , Malkowska-Lanzafame A. , Kaczmarek E.

Folia Morphologica

2015

tom 74

nr 1

Background: Several studies have shown increased serum levels of proinflammatory cytokines (IL-1α, IL-6 and TNF-α) in patients with cholelithiasis. The local expression of the proteins involved in pathogenesis of the disease is poorly recognised. Materials and methods: The authors examined immunohistochemically (IHC) the expression status of IL-1α, IL-6, and TNF-α in gallbladder mucosa of the patients with cholelithiasis as related to acute (ACC) and chronic (CCC) types of cholecystitis. Proinflammatory cytokines were quantitatively evaluated in gallbladder mucosa (epithelium and lamina propria) in ACC (n = 16) and CCC (n = 55) groups using modern spatial visualisation technique. Results: Quantitative analysis of IHC signals showed no significant differences in IL-1α and IL-6 immunoexpression in patients with ACC and CCC. A significantly greater IHC expression of TNF-α was detected in CCC as compared with ACC group. In either of the patient groups immunoexpression of IL-1α and of TNF-α was significantly higher than that of IL-6. Immunoexpression of TNF-α was significantly higher than that of IL-1α only in CCC group. A positive correlation was disclosed between IHC expression of IL-1α and body mass index in CCC group. IHC expression of TNF-α correlated positively with expression of CD68 molecule (histiocytic marker), number of leukocytes in blood and higher grading of gallbladder wall in ACC group. Conclusions: A more pronounced IHC expression of TNF-α and IL-1α than IL-6 in both types of cholecystitis may suggest the role of these cytokines in pathogenesis of cholelithiasis. IHC expression of TNF-α shows better correlation with clinical/laboratory data in acute cholecystitis, and its quantitative prevalence over the remaining cytokines points to the role of the TNF-α in maintenance of inflammation in the course of cholelithiasis. (Folia Morphol 2015; 74, 1: 65–72)

CD3plus/CD16plusCD56plus cell numbers in peripheral blood are correlated with higher tumor burden in patients with diffuse large B-cell lymphoma

51%

Hus I. , Staroslawska E. , Bojarska-Junak A. , Dobrzynska-Rutkowska A. , Surdacka A. , Wdowiak P. , Wasiak M. , Kusz M. , Twardosz A. , Dmoszynska A. , Rolinski J.

tom 49

nr 1