The knowledge of residual stress distribution is of great importance from the viewpoint of both, industrial and basal research. The most commonly utilized method of residual stress determination is based on strain measurements near the drilled holes of known geometry made by means of tensometric rosettes. An alternative to tensometers way of strain measurement is Digital Image Correlation (DIC). This optical method utilizes digital images registered during observed object deformation and delivers results in the form of displacement field maps consisting of hundreds or thousands of data points. Therefore, it is possible to deliver much more data in comparison to rosettes (only 3 or 6 tensometers, usually) and use them in the inverse method numeric procedure for residual stress calculations. In the paper the experimental stand consisting of micro driller and stereo imaging system for 3D DIC measurement and its application to residual stress estimation in prestrained steel samples are presented followed by obtained results discussion.
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The present study is devoted to examinations of the elastic modulus with the use of the uniaxial tensile test. The commertial purity titanium Grade 2 in the two states i.e. microcrystalline (mc-Ti) and nanocrystalline (nc-Ti) were examined. Bulk nc-Ti was fabricated by hydrostatic extrusion (HE) which is one of the severe plastic deformation methods (SPD). The elastic modulus of mc-Ti and nc-Ti were compared with the aim to analyze the influence of the nanostructure of titanium on its elastic modulus. The mc-Ti and nc-Ti samples were subjected to uniaxial tensile tests at various strain rates and various values of stress. Generally, higher elastic modulus values were obtained in microcrystalline titanium. The elastic modulus of mc-Ti was evaluated at 107 GPa on average, whereas the elastic modulus of nc-Ti was 94 GPa on average. The nanocrystalline titanium had a lower elastic modulus than its microcrystalline counterpart by 13% on average, which can be attributed to the presence of significant volume of amorphous regions in the structure. Moreover, in this case a lower standard deviation of all the results was obtained. In most cases, with higher applied stress (load) the value of the modulus was lower, whereas at higher strain rates its value was higher.
Celem niniejszej pracy było zaprojektowanie i otrzymanie wstrzykiwalnego biomateriału o własnościach osteokondukcyjnych, który potencjalnie mógłby znaleźć zastosowanie w procesach augmentacji kości przed leczeniem implantologicznym z wykorzystaniem sterowanej regeneracji kości (GBR). W tym celu opracowano samoorganizujący się biomateriał otrzymany z granulatu chitozan/fosforan trójwapnia oraz soli sodowej kwasu alginowego (CH/TCP/Alg). Opracowany materiał przebadano pod względem morfologii i mikrostruktury, zarówno granulatu, jak i uformowanych aglomeratów. Własności fizyczne, takie jak czas żelowania oraz wytrzymałość mechaniczna na ściskanie były przedmiotem niniejszych badań. Przeprowadzono także testy in vivo opracowanego biomateriału na modelu szczura. Dokonano oceny odpowiedzi modelu zwierzęcego na zaimplantowany biomateriał, a wyniki porównano z alloplastycznym materiałem komercyjnie dostępnym. Otrzymane wyniki wskazały, że opracowany wstrzykiwalny system spełnia wymagania pod kątem zastosowań w sterowanej regeneracji kości.
EN
The main objective of the work was to design and fabricate an injectable biomaterial with osteoconductive properties for bone augmentation and potential to be used in dental applications in peri-implant therapy concerning guided bone regeneration. For this purpose, a self-setting biomaterial consisting of chitosan/ tricalcium phosphate microparticles and sodium alginate was formulated (CH/TCP/Alg). The obtained material was characterized as far as microsphere and formed agglomerates morphology and microstructure. Physical properties relating to setting time and mechanical properties were also investigated. Finally, in vivo response to implanted biomaterial was studied on rat model and compared with commercially available alloplastic material. The obtained results showed that designed injectable biomaterial fulfilled main requirements for guided bone regeneration application.
The main objective of the work was to design and fabricate an injectable biomaterial with osteoconductive properties that can be used in dental applications in peri-implant therapy concerning guided bone regeneration. For that purpose, a self-setting biomaterial consisting of chitosan/tricalcium phosphate microparticles and sodium alginate was formulated. The obtained material was characterized regarding microsphere and formed agglomerates morphology and microstructure. Physical properties, relating to setting time and mechanical properties, were also investigated. Finally, in vivo response to implanted biomaterial was studied on a rat model and compared with commercially available alloplastic material. The results showed that designed injectable biomaterial fulfi lled main requirements for guided bone regeneration application.
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Alloplastic bone substitute materials are raising some more interest as an alternative for autologic transplants and xenogenic materials especially in oral surgery over the last few years. These non-immunogenic and completely resorbable biomaterials are the basis for complete and predictable guided bone regeneration. In the majority of cases, such a material is chosen because of its convenient application by surgeons. The main objective of our project was to design and fabricate an osteoconductive, injectable and readily tolerable by human tissues biomaterial for guided bone regeneration. For this purpose, a self-setting composite consisting of chitosan/tricalcium phosphate microparticles and sodium alginate was made. The material obtained was characterized by microsphere and agglomerate morphology and microstructure. Its features relating to setting time and mechanical properties were precisely investigated. Our material was also evaluated according to PN-EN ISO 10993 Biological evaluation of medical devices, i.e., the in vitro tests for genotoxicity and cytotoxicity were conduced. Then, the following examinations were performed: subchronic systemic toxicity, skin sensitization, irritation and delayed-type hypersensitivity and local effects after implantation. The material tested showed a high degree of cytocompatibility, fulfilled the requirements of International Standards and seemed to be a "user friendly" material for oral surgeons.
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