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3 Otolaryngologia Polska

3 2018

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Submucosal bipolar radiofrequency therapy for treatment of turbinate hypertrophy

100%

Łuczaj J. , Rogowski M.

Otolaryngologia Polska

2007

tom 61(3)

290-294

Disturbance of nasal airflow occurs in about 30% of human population. Turbinate hypertrophy is frequently the base of many nasal obturative diseases. The aim of this study was to determine short- term and long term effects of the radiofrequency therapy (RFT) for patients with turbinate hypertrophy. Forty- one patients with inferior turbinate hypertrophy (19 females and 22 males) were enrolled in this study prospectively. The examination included: rhinoscopy, subiective visual analogue scale (VAS) score, in which a patient described his symptoms in points from 0, (always very good nasal airflow) to 10 points (always total obstruction) and anterior rhinomanometry. The clinical assessment was before radiofrequency-turbinectomy and within the days 7 to 25 afther this therapy (follow-up 1) and 12 months later (follow-up 2). RFT was performed in local anesthesia (1% Lidocain) by means of CELON. Rhinoscopy before RFT revealed turbinate hypertrophy, which was decreased in the follow-up examination. Subjective improvement of nasal airflow was felt by 39 patients (95%) at follow–up 1. At follow–up 2 fifteen patients (37%) reported a decreased nasal airflow when compared with the follow-up 1. Rhinomanometric results were better at follow-up 1 for the left side (p = 0,0003), the right side (p = 0,0002) and both sides altogether (p = 0,0001). The improvement continued at follow-up 2 for the left side (p = 0,0004), the right side (p = 0,001) and both sides (p = 0,001) when compared with rhinomanometry before RFT. There were not statistically significant differences between the rhinomanometric results at follow–up 1 and follow-up 2. Bipolar radiofrequency thermal ablation is an effective method for the therapy of turbinate hypertrophy.

Actinomycosis of sinus maxillaris – case report

80%

Biszewska J. , Różańska-Kudelska M. , Rogowski M. , Michalczuk I.

Otolaryngologia Polska

2008

tom 62(6)

782-783

The authors present the case of primary actinomycosis of maxillary sinus. The frequency of the disease, differential diagnosis and treatment we present.

Cysteinyl leukotriene 1 receptor expression in nasal polyps

70%

Różańska M. , Bielecki P. , Reszeć J. , Kowal K. , Rogowski M.

Otolaryngologia Polska

2018

tom 72(6)

17-22

Cysteinyl leukotrienes (CysLTs) have been implicated in the pathogenesis of chronic rhinosinusitis (CRS). This study was undertaken to better understand the role of CysLTs in the development of CRS through 1). assessment of the pattern of expression of CysLT1 receptor in nasal polyps from patients with CRS and 2). correlation of expression of CysLT1 receptor with clinical features. Expression of CysLT1 receptor was evaluated immunohistochemically in nasal polyps from 20 patients with CRS and nasal mucosa from 10 control subject undergoing plastic surgery of the nose. Patients with CRS showed significantly higher expression of CysLT1 receptor as compared with the control group (p<0.05). The expression of CysLT1 receptor in sub-epithelial inflammatory infiltrates tended to be higher in patients with CRS and allergy as compared with patients with CRS but without allergy (p=0.07). In particular, the expression of CysLT1 receptor in sub-epithelial inflammatory infiltrates was significantly greater in 3 patients with CRS and drug allergy as compared with patients with CRS but without drug allergy (p=0.03). Increased expression of CysLT1 receptor in inflamed mucosa of nasal polyps in patients with allergy might suggest particular role of CysLTs in the pathogenesis of nasal polyps in this group of patients.