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Vitae medicorum Gedanensium – rękopis z połowy XVIII w. ze zbiorów Biblioteki Gdańskiej Polskiej Akademii Nauk

100%

Siek B. , Szarszewski A.

Studia Źródłoznawcze. Commentationes

2015

tom 53

Vitae medicorumGedanensium – a Manuscript from the Mid–eighteenth Century in the Collections of the Gdańsk Library of the Polish Academy of SciencesOne of the most interesting archival sources for the history of medicine in Gdańsk is a manuscript in the Gdańsk Library of the Polish Academy of Sciences (Ms514), containing biographies of local physicians. Vitae medicorum Gedanensium, qui tum apudsuos tum apudexteros floruerunt originates from the library of V. Schlieff (1680–1750) and is attributed to the Gdańsk physician L. von Hammen (1651–1689). An analysis of the source, however, leads to the conclusion that this is a copy of the von Hammen manuscript in an unknown handwriting. The handwriting of the numerous later supplements is that of von Hammen, with Schlieff expanding the information in the biogrammes. The dictionary contains data about 82 Gdańsk physicians from the second quarter of the sixteenth century to the early eighteenth century, arranged in chronological order, and was not completed due to the death of the author. This is a valuable contribution to the history of medicine in Gdańsk, in particular after it was supplemented by Schlieff, who benefitted from a more copious range of sources than the one at the disposal of his predecessor.

Do parents properly assess children’s physical activity level? Study of over 20 thousand children and parents dyads

70%

Metelska P. , Brzeziński M. , Jankowski M. , Niedzielska A. , Szarszewski A.

European Journal of Translational and Clinical Medicine

2021

tom 4

nr 2

52-59

Background: From the public health perspective, it is particularly important to establish links between a persons' perception of their own health and their predispositions to undertake pro-health behaviours that enable them to maintain proper functioning of their body. In the case of the paediatric population, it is crucial to emphasise that adults are responsible for the adoption and development of appropriate health-enhancing behaviours by children. The aim of this study is to verify parents' perception of the level of children’s physical activity (PA) in comparison with objective measures describing children's physical fitness. Material and methods: Material for analysis consists of the results of anthropometric tests and cardiopulmonary exercise capacity of children as well as questionnaires concerning 28,891 children completed by parents. Results: In more than 40% of the sample, the subjectively assessed level of PA was not consistent with the cardiorespiratory fitness level. It was observed that the correct assessment of the level of PA of children is more common for girls, increases with the age of the child and with the level of parental education.

Helicobacter pylori increases expression of proapoptotic markers Fas and FasL on CD4 lymphocytes in children

51%

Kotłowska-Kmieć A. , Bąkowska A. , Szarszewski A. , Kamińska B. , Łuczak G. , Radys W. , Landowski P. , Brodzicki J. , Korzon M. , Liberek A.

Acta Biochimica Polonica

2009

tom 56

nr 3

433-438

The pathomechanism of Helicobacter pylori action upon gastric mucosa and its role in the pathogenesis of gastritis have not been fully elucidated. The aim of this study was to evaluate the most prevalent lymphocyte subpopulations of the gastric mucosa in gastritis in children, as well as to evaluate the expression of Fas and Fas ligand receptors (FasL), periapoptotic markers of gastric mucosa lymphocytes before and after H. pylori eradication. Forty nine patients aged 6 to 17 years, investigated due to chronic abdominal pain, were studied. The obtained tissue samples were analysed by immunohistochemistry. Different lymphocyte subsets were quantified on the basis of surface antigen expression (CD3, CD4, CD8, CD20), secreted cytokines (IL-4, IL-6, IFNγ) and Fas and FasL proteins in the gastric mucosa. B and T helper lymphocytes were found to play a major role in the inflammatory infiltration in the gastric mucosa in children during H. pylori infection. Their expression was found to decrease after eradication. The enhanced expression of Fas receptor on lymphocytes before treatment and a decrease of this expression after eradication of H. pylori were shown. It was demonstrated that there is a correlation between CD4 and Fas receptor expression that may induce apoptosis of the helper lymphocytes in infected children.