Wyniki wyszukiwania - Biblioteka Nauki

Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

Ograniczanie wyników

3 Polish Journal of Otolaryngology

Znaleziono wyników: 3

Liczba wyników na stronie

Wyniki wyszukiwania

Sortuj według:

Ogranicz wyniki do:

Intranasal steroid therapy – EPOS 2020

100%

Rot P. , Rapiejko P. , Jurkiewicz D.

nr 3

41-49

Introduction: Due to their strong, multidirectional anti-inflammatory activity, intranasal glucocorticoids are the mainstay of treatment in rhinosinusitis, including acute rhinosinusitis, chronic rhinosinusitis, and chronic rhinosinusitis with nasal polyps, as well as allergic rhinitis. Owing to its high systemic safety and high anti-inflammatory efficacy, mometasone furoate – a new-generation intranasal glucocorticoid – was approved in 2019 as an over-the-counter (OTC) medication for Polish patients diagnosed with allergic rhinitis. Scientific societies and expert groups recommend the use of intranasal glucocorticoids in a much broader range of indications. In February 2020, an updated version of the European Position Paper on Rhinosinusitis and Nasal Polyps (EPOS 2020) was published. Aim: This article discusses the role of nasal glucocorticoids in regimens used in the treatment of nasal sinusitis as published in EPOS 2020 with Polish country-specific realities being taken into account.

Biologicals in the treatment of chronic rhinosinusitis with nasal polyps – position of the Polish Society of Otorhinolaryngologists – Head and Neck Surgeons and the Polish Society of Allergology experts

100%

Jurkiewicz D. , Kupczyk M. , Brożek-Mądry E. , Rapiejko P.

nr 2

1-11

Przewlekłe zapalenie błony śluzowej nosa i zatok przynosowych z polipami nosa (PZZPzPN) wywiera duży wpływ na samopoczucie i funkcje społeczne chorego. Uogólniony proces zapalny przebiegający z powstawaniem polipów nosa i nadmiarem eozynofilów w obrębie błony śluzowej zatok przynosowych to zapalenie typu 2., w którym pośredniczą limfocyty Th2 – komórki układu immunologicznego, odpowiadające za przewlekłe procesy zapalne. Dziś znamy też kluczowe mediatory prozapalne, przeciwko którym powstały nowe leki, tzw. leki biologiczne, wytwarzane w liniach komórkowych. W dokumencie przedstawiamy dostępne, w obecnej chwili, leczenie biologiczne zatwierdzone do leczenia pacjentów z T2 – zależnym przewlekłym zapaleniem zatok przynosowych.

Chronic rhinosinusitis with nasal polyps (CRSwNP) has a significant impact on the well-being and social functions of the patient. The generalized inflammatory process with the formation of nasal polyps and excess eosinophils in the mucosa of the paranasal sinuses is called type 2 inflammation, which is mediated by Th2 lymphocytes – cells of the immune system responsible for chronic inflammatory processes. Today, we also know the key pro-inflammatory mediators against which new drugs have been developed, the so-called biological drugs, are produced in cell lines. In this document, we present currently available biologicals approved for the treatment of patients with T2-related chronic rhinosinusitis.

Drug-induced diseases in otolaryngology – causes, clinical signs, treatment

75%

Woroń J. , Jurkiewicz D. , Rapiejko P. , Lorkowska- Zawicka B. , Tymiński R. , Wordliczek J.

nr 5

9-15

Introduction: In the daily practice of an otolaryngologist, we encounter cases where the symptoms are not the result of disease but result from pharmacotherapy. In the case of symptoms such as hearing loss, tinnitus, or dizziness, polytherapy may be used as the basis for their occurrence, which, due to the lack of rationality in combining drugs, leads to symptoms that the patient and the doctor very often interpret as a new disease syndrome. Aim: The aim of the study is to show and to raise awareness of the fact that the symptoms of hearing organ impairment are frequently drug-related and only a modification of the currently used pharmacotherapy is a rational procedure in such cases. Material: This paper describes 30 cases who developed side effects of polypharmacy in the form of hearing disorders, dizziness, and tinnitus. The causes of drug-related complications were discussed, as well as effective methods of their prevention.