Immunotherapy of type 1 diabetes

• Autorzy: L. Li , Z. Yi , R. Tisch , B. Wang
• Języki publikacji: EN

Abstrakty

EN

Type 1 diabetes (T1D) is an autoimmune disease in which the insulin-producing beta cells are destroyed. Diabetic patients manage their hyperglycemia by daily insulin injections. However, insulin therapy is by no means a cure. Accordingly, a significant effort has been ongoing to develop immunotherapies that effectively prevent and/or treat T1D in the clinic. This review focuses on antigen- and antibody-based immunotherapies and discusses the respective strengths and weaknesses of these approaches.

Słowa kluczowe

EN

ANTIBODY; ANTIGEN; IMMUNOREGULATORY; T CELL; TOLERANCE

• Czasopismo: Archivum Immunologiae et Therapiae Experimentalis
• Rocznik: 2008
• Tom: 56
• Numer: 4
• Strony: 227-236

Twórcy

autor

L. Li

autor

Z. Yi

autor

R. Tisch

autor

B. Wang

• Typ dokumentu: REVIEW
• Bibliografia: Roland Tisch, Department of Microbiology and Immunology, Mary Ellen Jones Bldg., Room 635, Campus Box 7290, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-7290, USA