Warianty tytułu
Języki publikacji
Abstrakty
NO mediates many systemic reactions in humans and animals. It is produced by constitutive synthases (cNOS) and one inducible by cytokines and endotoxines (iNOS). We summarize, on the base of experimental and clinical data, the pathophysiological role of NO in septic shock as well as the effects of pharmacological application of NOS inhibitors. The analysed data show, that the contribution of NO to the pathomechanism of septic shock is rather heterogenous, therefore the clinical therapeutical application of selective iNOS inhibitors is impossible without adequate new monitoring tools.
Słowa kluczowe
Czasopismo
Rocznik
Tom
Numer
Strony
67-90
Opis fizyczny
Twórcy
Bibliografia
Typ dokumentu
ARTICLE
Bibliografia
G. Jonderko, Katedra i Oddzial Kliniczny Chorob Wewnetrznych Slaska Akademia Medyczna, ul. Edukacji 102, 43-100 Tychy, Poland
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Identyfikator YADDA
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