Effect of outer membrane proteins from Shigella humoral immunity induced in mice by SRBC

• Autorzy: Anna Czarny , Danuta Witkowska , Marian Mulczyk
• Języki publikacji: EN

Abstrakty

EN

Shigella flexneri outer membrane proteins (OMP) which had been earlier found to exert immunomodulatory effect on cell mediated immune response were also found to act as immunomodulator of the humoral immune response. Effects of OMP were investigated in the experiments in vitro and in vivo, where the level of humoral immune response measured as the number of plaque-forming cells (PFC) to SRBC in the spleen was evaluated. We demnostrate that small doses of OMP stimulate, whereas higher doses suppress the humoral immunity.

Słowa kluczowe

EN

IMMUNITY; MEMBRANE PROTEIN; MOUSE; SHIGELLA

• Czasopismo: Archivum Immunologiae et Therapiae Experimentalis
• Rocznik: 1992
• Tom: 40
• Numer: 2
• Strony: 129-134

Twórcy

autor

Anna Czarny

autor

Danuta Witkowska

autor

Marian Mulczyk

• Typ dokumentu: article