DNA microarrays in structural and functional genomics

• Autorzy: A. Zmienko , L. Handschuh , M. Goralski , M. Figlerowicz
• Języki publikacji: PL

Abstrakty

EN

DNA microarrays or DNA chips were introduced in the middle nineties and have developed as a very powerful tool for structural and functional analysis of genomes. With thousands to millions of probes deposited on each microarray, it is now possible to perform various kinds of analysis on the genome-wide scale. The basic use of microarrays is gene expression profiling. For this purpose, both one- and two-color labeling methods are used. More sophisticated DNA microarrays allow for analyzing alternative splicing, DNA-protein interactions, chromatine modifications and many more. Currently, DNA microarrays represent an indispensable tool in biology and medicine.

Słowa kluczowe

EN

DNA CHIP; GENE EXPRESSION; MICROARRAY

• Czasopismo: Biotechnologia
• Rocznik: 2008
• Numer: 4
• Strony: 39-53

Twórcy

autor

A. Zmienko

autor

L. Handschuh

autor

M. Goralski

autor

M. Figlerowicz

• Typ dokumentu: REVIEW
• Bibliografia: Agnieszka Zmienko, Instytut Chemii Bioorganicznej, Polska Akademia Nauk, ul. Noskowskiego 12/14, 61-704 Poznan, Poland