Risk of Severe hypoglycaemia for Various Treatment Regimens - A Systematic Review and Meta-analysis of Observational Studies

• Autorzy: Michał Jakubczyk , Justyna Pawęska , Maciej Niewada , Elżbieta Rdzanek , Marcin Czech
• Języki publikacji: EN

Abstrakty

EN

Previous publications show that diabetes mellitus (DM) is a grave medical and economic problem, largely due to complications. The objective is to evaluate real-life risk of severe hypoglycaemic events (SHEs) among diabetic patients (type 1 and 2, T1&2) for various therapies. We conducted a systematic review of observational studies in MEDLINE, Embase, and The Cochrane Library databases. Observational, retrospective or prospective, studies (with at least 100 participants) in children and adults were included, with focus on: time horizon, number of patients, number of SHEs, and number of patients experiencing SHEs. In T1 DM we distinguished basal-bolus/pre-mix insulin and insulin pump, and in T2 DM we singled out basal-bolus/pre-mix insulin, basal supported oral therapy with insulin as the basal component, sulfonylurea, and other antidiabetic medications(original abstract)

Słowa kluczowe

PL

Choroby; Leczenie; Medycyna

EN

Illness; Medical treatment; Medicine

• Czasopismo: Journal of Health Policy and Outcomes Research
• Rocznik: 2014
• Numer: nr 2
• Strony: 76-93

Twórcy

autor

Michał Jakubczyk

• Warsaw School of Economics, Poland

autor

Justyna Pawęska

• HealthQuest spółka z ograniczoną odpowiedzialnością Sp. K, Warsaw, Poland

autor

Maciej Niewada

• Medical University of Warsaw, Poland

autor

Elżbieta Rdzanek

• HealthQuest spółka z ograniczoną odpowiedzialnością Sp. K, Warsaw, Poland

autor

Marcin Czech

• Novo Nordisk Pharma sp. z o.o.

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Identyfikatory

DOI

10.7365/JHPOR.2014.2.9