Lead II electrocardiograph-derived entropy index for autonomic function assessment in type 2 diabetes mellitus

• Autorzy: Yang, Shanglin , Liao, Xuwei , Lin, Yuyang , Chen, Jianjung , Wu, Hsientsai
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to introduce and evaluate the baroreflex entropy index (BEI), a novel tool derived from standard lead II electrocardiograph (EKG) for autonomic function (AF) assessment in type 2 diabetes mellitus (T2DM). Researchers with distinct roles (analysis and data preparation) analyzed anonymized EKG data from healthy controls and two patient groups with T2DM (well controlled and poorly controlled). BEI was compared between groups, and correlations with glycemic markers (HbA1c, fasting glucose) were investigated. Logistic regression was used to assess the association between BEI and T2DM risk. BEI showed good repeatability and differentiation between groups. Notably, it required only single-lead EKG. BEI was inversely correlated with glycemic markers, suggesting improved baroreflex regulation with better glycemic control. BEI also out-performed small-scale multiscale entropy in group discrimination. Logistic regression identified BEI as a protective factor for T2DM. BEI represents a promising tool for monitoring AF, assessing glycemic control, and potentially stratifying T2DM risk. Further validation in larger longitudinal studies and an exploration of the applicability of BEI to other diseases are warranted.

Słowa kluczowe

PL

BEI; funkcja autonomiczna; odstęp RR; cukrzyca typu 2

EN

baroreflex entropy index; BEI; autonomic function; AF; lead II EKG; R wave amplitude; RR interval; type 2 diabetes mellitus; T2DM

• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2024
• Tom: Vol. 44, no. 3
• Strony: 513--520
• Opis fizyczny: Bibliogr. 43 poz., rys., tab., wykr.

Twórcy

autor

Yang, Shanglin

• School of Electrical and Information Engineering, North Minzu University, No. 204 North Wenchang Street, Yinchuan, Ningxia 750021, China,
• Microelectronics and Solid-State Electronics Device Research Center, North Minzu University, Yinchuan, Ningxia 750021, China

autor

Liao, Xuwei

• School of Electrical and Information Engineering, North Minzu University, No. 204 North Wenchang Street, Yinchuan, Ningxia 750021, China,

autor

Lin, Yuyang

• School of Electrical and Information Engineering, North Minzu University, No. 204 North Wenchang Street, Yinchuan, Ningxia 750021, China,

autor

Chen, Jianjung

• Taichung Tzuchi Hospital, The Buddhist Tzuchi Medical Foundation, Taichung 42743, Taiwan,

autor

Wu, Hsientsai

• School of Electrical and Information Engineering, North Minzu University, No. 204 North Wenchang Street, Yinchuan, Ningxia 750021, China,
• Department of Electrical Engineering, Dong Hwa University, No. 1, Section 2, Da Hsueh Rd., Hualien 97401, Taiwan

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Identyfikatory

DOI

10.1016/j.bbe.2024.08.002