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Abstrakty
N-chloropyrazinamide was prepared by the chlorination of pyrazinamide using trichloroisocyanuric acid. The experimental results ascertained that the tested N-chloropyrazinamide showed good antimicrobial activities when compared to standard drug. It was found that N-chloropyrazinamide at different concentrations exhibited significant dose dependent anti-oxidant, anti-inflammatory and anti-hypertensive activity.
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1--8
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Bibliogr. 20 poz., tab.
Twórcy
autor
- Department of Chemistry, M.A.M. College of Engineering and Technology, Siruganur, Tiruchirappalli - 621 105, Tamil Nadu, India, spv.sjc@gmail.com
autor
- Department of Chemistry, Jayaram College of Engineering and Technology, Karattampatti - Pagalavadi, Thuraiyur (Tk), Tiruchirappalli - 621 014, Tamil Nadu, India
Bibliografia
- [1] Michael H. Cynamon, Sally P. Klemens, Tso Sheng Chou, Rayomand H. Gimi, John T. Welch, Journal of Medicinal Chemistry 35 (1992) 1212-1215.
- [2] Setsuko Yamamoto, Ichiro Toida, Nanao Watanabe, Toshikazu Ura, Antimicrobial Agents and Chemotherapy 39(9) (1995) 2088-2091.
- [3] Veronika Opletalova, Jiri Hartl, Asmita Patel, Karel Palat Jr, Vladimir Buchta, Farmaco 57 (2002) 135-144.
- [4] Martin Dolezal, Lenka Tumova, Diana Kesetovicova, Jiri Tuma, Katarina Kraloya, Molecules 12(12) (2007) 2589-2598.
- [5] Martin Dolezal, Lukas Palek, Jarmila Vinsova, Vladimir Buchta, Josef Jampilek, Katarina Kraloya, Molecules 11(4) (2006) 242-256.
- [6] A. W. Cuthbert, J. M. Edwardson, Journal of Pharmacy and Pharmacology 31(6) (1979) 382-386.
- [7] B. A. Ellsworth, et. al., Bioorganic Medicinal Chemistry Letters 17(14) (2007) 3978-3982.
- [8] Martin Dolezal, Jan Zitko, Diana Kesetovicova, Jiri Kunes, Michaela Svobodova, Molecules 14(10) (2009) 4180-4189.
- [9] Lenka Tumova, Jiri Tuma, Klara Megusar, Marin Dolezal, Molecules 15(1) (2010) 331-340.
- [10] M. Dolezal, J. Zitko, Z. Osicka, J. Kunes, M. Vejsova, V. Buchta, J. Dohnal, J. Jampilek, K. Kralova, Molecules 15(12) (2010) 8567-8581.
- [11] Lenka Tumova, Jiri Tuma, Martin Dolezal, Molecules 16(11) (2011) 9142-9152.
- [12] S. Suzuki, A. Inoue, Chemical Abstracts 113 (1990) 218276t.
- [13] T. Sado, A. Inoue, Chemical Abstracts 113 (1990) 78422k.
- [14] Talaat Ibrahim El-Emary, Journal of Chinese Chemical Society 53(2) (2006) 391-401.
- [15] H. S. El-Kashef, T. I. El-Emary, M. Gasquet, P. Timon-David, J. Maldonado, P. Vanelle, Pharmazie 55(8) (2000) 572-576.
- [16] S. Parimala Vaijayanthi, N. Mathiyalagan, International Journal of Research in Organic Chemistry 2(3) (2012) 13-15.
- [17] S. K. Ling, T. Tanaka, I. Kouno, Biological & Pharmaceutical Bulletin 26(3) (2003) 352-356.
- [18] S. Kumar, D. Kumar, Manjusha, K. Saroha, N. Singh, B. Vashishta, Acta Pharmaceutica 58 (2008) 215-220.
- [19] V. K. Jimsheena, Analytical Chemistry 81 (2009) 9388-9394.
- [20] Nigel M. Hooper, Anthony J. Turner, Biochemical Journal 241 (1987) 625-633.
Typ dokumentu
Bibliografia
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