Warianty tytułu
Konferencja
Symposium "From Molecular Recognition to Molecular Devices", September 20-22, Gdańsk, Poland
Języki publikacji
Abstrakty
Macrocycles can be synthesized under kinetic or thermodynamic control, the latter leading to mixtures in equilibrium. Their composition can be controlled by addition of templates. Alkaline earth metal ions have been used to synthesize imine macrocycles of different sizes from dialdehydes and diamines specifically. In addition, the competition between the formation of a macrocycle or a bimacrocyclic cage compound can be controlled by a proper template ion. Also organic templates such as polyols can be used to stabilize a resulting macrocycle. As recognition reaction, the formation of boronic esters is presented, the macrocyclization was achieved by ring-closing metathesis. Due to the templates, endo-functionalized macrocycles are achieved, such as concave acids or bases, metal ion complexes and even N-heterocyclic carbenes. All of these can be part of a concave structure which determines their reactivity and selectivity in reactions such as acid/base catalysis, metallo-or-organocatalysis.
Czasopismo
Rocznik
Tom
Strony
1161-1174
Opis fizyczny
Bibliogr. 64 poz., rys.
Twórcy
autor
- Otto-Diels-Institut für Organische Chemie, Chris tian-Albrechts-Universität zu Kiel,Olshausenstr. 40, D - 24098 Kiel, Germany Fax: +49 431/880-1558, luening@oc.uni-kiel.de
Bibliografia
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- 29. For a very recent example of a templated macrocyclization using imine chemistry to bind the template, see: Albrecht M., Veni A. and Fröhlich R., Synlett, 2295 (2007).
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- 56. A recent review on thiamine-dependent enzymes: Duggleby R., Acc. Chem. Res., 550 (2006).
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- 62. Winkelmann O., Näther C. and Lüning U., Eur. J. Org. Chem., 981 (2007).
- 63. Winkelmann O., Lindner D., Lacour J., Nather C. and Lüning U., Eur. J. Org. Chem., 3687 (2007).
- 64. Winkelmann O., Nather C. and Lüning U., J. Organomet. Chem., (2008), doi: 10.1016/j.jorganchem.2007.11.064.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
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