Reactions of Chlorinated Pyrimidine Derivatives with Carbanions Bearing Nucleophugal Groups at the Carbanionic Center

• Autorzy: Mąkosza, M. , Ostrowski, S.
• Języki publikacji: EN

Abstrakty

EN

Reactions of chloro-, dichloro-, and trichloropyrimidines with carbanions bearing leaving groups at the carbanionic center are described. 2-Chloropyrimidine and 2,4-dichloropyrimidine react at low temperature with trihalomethyl carbanions to give covalent sigma-adducts and low yield of the Vicarious Nucleophilic Substitution of Hydrogen (VNS) products. 4,5,6-Trichloropyrimidine in the reactions with carbanions (–CH(X)SO2Tol, CBr-3) or other nucleophiles (t-BuO–, NH3) gives diverse substituted products of chlorine while in the reaction with CC-3 anion the VNS product in small amount.

• Czasopismo: Polish Journal of Chemistry
• Rocznik: 2000
• Tom: Vol. 74, nr 10
• Strony: 1355-1355
• Opis fizyczny: –1361, Bibliogr. 15 poz., rys.

Twórcy

autor

Mąkosza, M.

autor

Ostrowski, S.

• Institute of Organic Chemistry, Polish Academy of Sciences, ul. Kasprzaka 44/52, PL-01-224 Warszawa, Poland,