Warianty tytułu
Zastosowanie mieszanin gaussowskich oraz proteomicznych baz danych w analizie widm masowych – architektura systemu informatycznego kompleksowego przetwarzania danych spektrometrycznych
Języki publikacji
Abstrakty
This paper presents assumptions of the protein mass spectra analysis software. All the spectra are modeled with Gaussian Mixture Models. Estimation of model parameters is done by means of an Expectation-Maximization algorithm. The obtained parameters are used for a further biological analysis. The software is integrated with four huge protein databases available on-line. The biological information about proteins may be achieved on the chosen level of some detail.
Artykuł przedstawia założenia systemu służącego analizie widm masowych białek. Widma są modelowane za pomocą mieszanin rozkładów normalnych. Oszacowanie ich parametrów oparte jest na algorytmie Expectation-Maximization. Uzyskane parametry są poddawane dalszej analizie biologicznej. System jest zintegrowany z czterema dużymi białkowymi bazami danych dostępnymi on-line. Informacja biologiczna dotycząca zawartych w widmie białek może być uzyskana na wybranym stopniu szczegółowości.
Czasopismo
Rocznik
Tom
Strony
289-302
Opis fizyczny
Bibliogr. 30 poz.
Twórcy
autor
- Politechnika Lubelska, Instytut Informatyki, gosiap@cs.pollub.pl
Bibliografia
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.baztech-article-BSL7-0046-0028