Analytical microsystems for biomedical and environmental applications

• Autorzy: Jaffrezic-Renault, N. , Errachid , A.
• Języki publikacji: EN

Abstrakty

EN

Two types of analytical microsystems for the detection of species of interest in biomedical diagnosis and in environmental monitoring are specifically described in this paper. We describe a novel device that will measure whole blood concentration of D-dimer, a recognized biomarker of increased blood clotting activity and that will then offer opportunity to use the test in the point of care setting. The device combines innovation in antibody bio-engineering for high specificity immunoassay-based diagnostics and nano/micro engineered impedimetric analysis electrodes incorporating a biocompatible polymer substrate with development of a disposable microfluidic manifold, enabling diagnostics at the point-of-first-contact. The feasibility of a generic microsystem integrating a microfluidic system of concentration and a module of electrochemical detection is demonstrated for the four metals of the European directive (OCE 2000/GO/EC) for the quality of water resource: cadmium, mercury, lead and nickeI.

Słowa kluczowe

PL

mikroukład analityczny; elektrochemiczna spektroskopia impedancyjna; zakrzepica żył głębokich; gospodarka wodna; metale ciężkie

EN

analytical microsystem; fluidic microsystem; electrochemical impedance spectroscopy; Deep Venous Thrombosis; water resource; heavy metals; diamond-like carbon

• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2011
• Tom: Vol. 31, no. 4
• Strony: 3-16
• Opis fizyczny: Bibliogr. 40 poz., rys., wykr.

Twórcy

autor

Jaffrezic-Renault, N.

autor

Errachid , A.

• University of Lyon, Laboratory of Analytical Sciences, Claude Bernard University Lyon 1, Building CPE, 43 Boulevard 11 Novembre 1918, 69622 Villeurbanne Cedex, France,

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