Spectral analysis of the EEG-signal registered during anaesthesia induced by propofol and maintained by fluorinated inhalation anaesthetics

• Autorzy: Olejarczyk, E. , Sobieszek, A. , Rudner, R. , Marciniak, R. , Wartak, M. , Stasiowski, M. , Jałowiecki, P.
• Języki publikacji: EN

Abstrakty

EN

The aim of this study was to identify the effects of different volatile anaesthetics (isoflurane, desflurane or sevoflurane) on the spectro-temporal pattern of EEG during all of the stages of anaesthesia recorded at the frontal derivations in 64 adult patients. The relative powers of EEG for delta, theta, alpha and beta frequency bands as well as the characteristics of their time evolution and their relationships with the concentrations of anaesthetics were used as the EEG spectra indices. The time evolutions of the individual wave powers in 75% of patients were similar for all the anaesthetics used in this study at the same method of administration. Well correlated biphasic changes in the slow and fast wave powers emerged after propofol induction as well as in association with the volatile anaesthetics action. Wave powers as well as their relationships with the anaesthetic concentrations were not hampered by the variability across the patients and anaesthetics used in this study. Comparing the branches of increasing and decreasing concentration, the hysteresis phenomenon, i.e. systematic decrease or increase of each wave power, was observed at the end of anaesthesia for each of the volatile anaesthetics. A rapid increase of sevoflurane concentration at the initial phase of anaesthesia caused more effective attenuation of beta waves than in the case of gradual anaesthetic administration but it happened at the cost of the intensification of delta waves.

Słowa kluczowe

PL

sygnał EEG; znieczulenie lotne; izofluran; desfluran; analiza spektralna

EN

EEG signal; volatile anaesthesia; fluorinated inhalation anaesthetics; isoflurane; desflurane; sevoflurane; spectral analysis; biphasic effect; hysteresis

• Czasopismo: Biocybernetics and Biomedical Engineering
• Rocznik: 2010
• Tom: Vol. 30, no. 1
• Strony: 55-70
• Opis fizyczny: Bibliogr. 9 poz., tab., wykr.

Twórcy

autor

Olejarczyk, E.

autor

Sobieszek, A.

autor

Rudner, R.

autor

Marciniak, R.

autor

Wartak, M.

autor

Stasiowski, M.

autor

Jałowiecki, P.

• Institute of Biocybernetics and Biomedical Engineering, Polish Academy of Sciences, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland,

Bibliografia

• 1. Lloyd-Thomas A.R., Cole P.V., Prior P.F.: Quantitative EEG and brainstem auditory evoked -potentials: comparison of isoflurane with halothane using the cerebral function analysing monitor. Br. J. Anaesth. 1990, 65, 306-312.
• 2. Kuizenga K., Wierda J.M., Kalkman C.J.: Biphasic EEG changes in relation to loss of consciousness during induction with thiopental, propofol, etomidate, midazolam or sevoflurane. Br. J. Anaesth. 2001, 86, 354-360.
• 3. Koskinen M., Mustola S., Seppanen T.: Relation of EEG spectrum progression to loss of responsiveness during induction of anesthesia with propofol. Clinical Neurophysiology 2005, 116, 2069-2076.
• 4. Kortelainen J., Koskinen M., Mustola S., Seppänen T.: EEG Frequency Progression during Induction of Anesthesia: from Start of Infusion to Onset of Burst Suppression Pattern. Conf. Proc. IEEE Eng. Med. Biol. Soc., 2007, 1570-1573.
• 5. Niedermeyer E., Lopes de Silva F.: Electroencephalography. Basic principles, clinical applications and related fields. Baltimore, Md: Williams & Wilkins, 1987.
• 6. Chatrian G.E., Bergamini L., Dondey M., Klass D.W., Lennox-Buchthal M., Petersen I.: International Federation of Societies for Electroencephalography and Clinical Neurophysiology. Appendix B: A glossary of terms most commonly used by clinical electroencephalographers. Electroenceph. Clin. Neuroph. 1974, 37, 521-553.
• 7. Olejarczyk E., Sobieszek A., Rudner R., Marciniak R., Wartak M., Stasiowski M., Jałowiecki P.: Evaluation of the EEG-signal during volatile anaesthesia: methodological approach. Biocybernetics and Biomedical Engineering, 2009, 29, 1, 3-28.
• 8. Olejarczyk E., Sobieszek A., Rudner R., Marciniak R., Wartak M., Stasiowski M., Jałowiecki P.: Characteristic features of the EEG patterns during anaesthesia evoked by fluorinated inhalation anaesthetics. 4th Eur. Cong. Intern. Feder. Med. Biol. Eng. 23-27 November 2008, Antwerp, Belgium.
• 9. Rundshagen I., Schroder T., Prichep L.S., John E.R., Kox W.J.: Changes in cortical electrical activity during induction of amaesthesia with thiopental/fentanyl and tracheal intubation: a quantitative electroencephalographic analysis. Br. J. Anaesth. 2004, 92, 33-38.