Synthesis of some 5-amino-2-methyl-4-nitro-1-phenacylimidazoles

• Autorzy: Sobiak, S.
• Języki publikacji: EN

Abstrakty

EN

Reaction of 4(5)-bromo-2-methyl-5(4)-nitroimidazole with phenacyl bromide derivatives gave two isomers: 4-bromo-5-niroimidazoles (4a-e) and 5-bromo-4-nitroimidazoles (5a-e). Compounds 5a-e were treated with cyclic secondary amines to afford expected 5-amino-4-nitroimidazole derivatives 6a-c - 10a-b.

Słowa kluczowe

EN

nitroimidazoles; bromonitroimidazoles; aminonitroimidazoles; anticancer; activity

• Czasopismo: Polish Journal of Chemistry
• Rocznik: 1998
• Tom: Vol. 72, nr 1
• Strony: 78-83
• Opis fizyczny: Bibliogr. 14 poz., tab., wykr.

Twórcy

autor

Sobiak, S.

• Department of Chemical Technology of Drugs Faculty of Pharmacy K. Marcinkowski University of Medical Sciences 60-780 Poznań Poland,