Biodegradowalne polimery otrzymane na bazie glikolidu, laktydu, epsylon-kaprolaktonu i TMC w długo-terminowym, kontrolowanym transporcie cyklosporyny A i sirolimusu

• Autorzy: Jelonek, K. , Kasperczyk, J. , Dobrzyński, P.

Warianty tytułu

EN

Biodegradable polymers based on glycolide, lactide, epsylon-caprolactone and TCM for long-term controlled delivery of cyclosporine A and sirolimus

• Języki publikacji: PL

Słowa kluczowe

PL

polimery biodegradowalne

EN

biodegradable polymers

• Czasopismo: Inżynieria Biomateriałów
• Rocznik: 2006
• Tom: R. 9, nr 58-60
• Strony: 129-132
• Opis fizyczny: Bibliogr. 9 poz., tekst pol.-ang.

Twórcy

autor

Jelonek, K.

• Katedra i Zakład Biofarmacji, Śląska Akademia Medyczna, Narcyzów 1, Sosnowiec 41-200, Polska

autor

Kasperczyk, J.

• Katedra i Zakład Biofarmacji, Śląska Akademia Medyczna, Narcyzów 1, Sosnowiec 41-200, Polska

autor

Dobrzyński, P.

• Polska Akademia Nauk, Centrum Chemii Polimerów, M. Skłodowskiej-Curie 34, Zabrze 41-819, Polska

Bibliografia

• [1] Pillai P., Panchagnula R: Polymers in drug delivery. Current opinion in Chemical Biology, 5 (2001), pp 447 - 451
• [2] Chacon M., Molperces ., Berges L., Guzman M., Aberturas M. R.: Stability and freeze - drying of cyclosporine loaded poly(D,L lactide - glycolide) carriers, European Journal of Pharmaceutical Science. 8(1999). pp 99 107
• [3] Gref R., Quellec P., Sanchez A., Calvo P., Dellacherie E., Alonso M. J.: Development and characterization of CyA-loaded poly(lactic acid)-poly(ethylene glycol) PEG micro- and nanoparticles. Comparison with conventional PLA particulate carriers. European Journal of Pharmaceutics and Biopharmaceutics, 51 (2001), pp 111 - 118
• [4] Alexis F., Venkatraman S., Rath S.K., Boey F.: In vitro study of release mechanisms of paclitaxel and rapamycin from drug - incorporated biodegradable stent matrices. Journal of Controlled Release 98 (2004), pp 67 - 74
• [5] Dobrzynski P., Kasperczyk J., Janeczek H., Bero M.: Synthesis of Biodegradable Copolymers with the Use of Low Toxic Zirconium Compounds. 1. Copolymerization of Glycolide with L-Lactide Initited by Zr(Acac)4, Macromolecules 2001, 34, 5090 - 5098
• [6] Kasperczyk. J.: Microstructural analysis of poly[(LL-lactide)-co-glycolide)] by 1H and 13C n.m.r. spectroscopy Polymer Vol 37, No 2, pp 201 - 203, 1996
• [7] P. Dobrzyński, S Li, J. Kasperczyk, M. Bero, F. Gasc, M. Vert, Structure - property relationships of copolymers obtained by ring - opening polymerization of glycolide and epsylon-caprolactone. Part 1. Synthesis and Characterization. Biomacromolecules 6 (2005) 483 - 488.
• [8] P. Dobrzyński, J. Kasperczyk, M. Bero, Synthesis of biodegradable copolymers with low-toxicity zirconium compounds V. Multiblock and random copolymers of L-lactide with trimethylene Carbonate obtained in copolymerization initiated with zirconium (IV) acetylacetonate. Journal of Polymer Science Part A: Polymer Chemistry, Vol. 44 (2006) 3184-3201; Published online in Wiley Inter Science (www.interscience.wiley.com)
• [9] J. Kasperczyk, M. Bero, The role of transesterification in the copolymerization of L,L-lactide and epsylon-caprolactone, Makromol. Chem. 194 (1993) 913-925.