Synthesis, Spectral Studies Antibacterial and Antifungal Activity of 2" – Amino - 4" - [2 - (4' -chlorophenyl)-6-methyl imidazo[1, 2-a] pyridin-3-yl]-6"-aryl Nicotinonitrile

• Autorzy: Bhuva, V. V. , Bhadani, V. N. , Purohit, H. D. , Purohit, D. M.
• Języki publikacji: EN

Abstrakty

EN

Pyridine nucleus plays an important role in medicine, agriculture and industrial chemistry. With a view of biological activities and variety of industrial applications, some new 2" – amino - 4" - [2 - (4' -chlorophenyl)-6-methyl imidazo [1, 2-a] pyridin-3-yl]-6"-aryl nicotinonitriles ( 4a-4l ) have been synthesized. The products have been assayed for their biological activity against Gram +ve, Gram –ve bacteria and fungi. Some of the products showed moderate activity in concentration 50μg/ml. The structures of the products have been elucidated by IR, 1H-NMR, Mass spectral data, elemental analysis and thin layer chromatography.

Słowa kluczowe

EN

2-Amino-3-Cyanopyridine; Antibacterial Activity; Antifungal Activity; Chalcone

• Czasopismo: International Letters of Chemistry, Physics and Astronomy
• Rocznik: 2015
• Tom: Vol. 49
• Strony: 161--166
• Opis fizyczny: Bibliogr. 13 poz., rys., tab., wz.

Twórcy

autor

Bhuva, V. V.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India

autor

Bhadani, V. N.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India

autor

Purohit, H. D.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India

autor

Purohit, D. M.

• Shree M. & N. Virani Science College, Department of Chemistry, Kalawad Road, Rajkot-360005, Gujarat, India,

Bibliografia

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Identyfikatory

DOI

10.18052/www.scipress.com/ILCPA.49.161