Efficient methods for synthesis of florol and its derivatives

• Autorzy: Jaśkowska, J. , Chorabik, K. , Majka, Z.

Warianty tytułu

PL

Opracowanie wydajnej metody syntezy florolu i jego pochodnych

• Języki publikacji: EN

Abstrakty

EN

The paper describes and compares the two methods of synthesis of florol (1) (4-methyl-2-(2-methylpropyl) tetrahydro-2H-pyran-4-ol) by the Prins reaction. The first method involves the reaction for obtaining 1 in methylene chloride as solvent at 60°C. The second method applies the preparation of florol (1) and other tetrahydrofuran derivatives in solvent-free conditions in room temperature.

PL

W pracy opisano i porównano dwie metody syntezy florolu (1) (4-methyl-2-(2-methylpropyl)tetrahydro2H-pyran-4-ol) na drodze reakcji Prinsa. Pierwsza metoda dotyczyła reakcji otrzymywania 1 w chlorku metylenu jako rozpuszczalniku w 60°C. Druga metoda, w warunkach bezrozpuszczalnikowych w temperaturze pokojowej, obejmowała zarówno syntezę florolu, jak i innych pochodnych tetrahydrofuranu.

Słowa kluczowe

PL

związki zapachowe; florifol; florol; synteza pochodnych tetrahydrofuranu; cyklizacja Prins'a

EN

fragrances; florol; florifol; synthesis of tetrahydropyran derivatives; Pins cyclisations

• Czasopismo: Czasopismo Techniczne. Chemia
• Rocznik: 2015
• Tom: R. 112, z. 1-Ch
• Strony: 29--36
• Opis fizyczny: Bibliogr. 12 poz., wz., tab.

Twórcy

autor

Jaśkowska, J.

• Institute of Organic Chemistry and Technology, Cracow University of Technology

autor

Chorabik, K.

• Institute of Organic Chemistry and Technology, Cracow University of Technology

autor

Majka, Z.

• Adamed Pharmaceuticals, Scientific Department

Bibliografia

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