Wydawca
Czasopismo
Rocznik
Tom
Numer
3
Identyfikatory
Okładka
Zawartość wolumenu
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3
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artykuł: Metabolic properties of purine and pyrimidine nucleoside analogues, active against HIV (Balzarini J.)
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artykuł: Hypoxanthine guanine phosphoribosyltransferase [HPRT] deficiency in Japanese and Korean (Yamada Y., Goto H., Nomura N., Kitoh H., Ogasawara N.)
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artykuł: The adenosine-induced mechanism for the acquisition of ischemic tolerance in primary rat neuronal cultures (Reshef A., Sperling O., Zoref-Shani E.)
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artykuł: Purine nucleotide catabolism in rat liver labelling of uric acid and allantoin after administration of various labelled precursors (Marinello E., Pagani R., Arezzini L., Porcelli B., Cinci G., Terzuoli L.)
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artykuł: Structure and function of ecto-nucleotidases and their role in the ischemic brain (Zimmermann H., Braun N., Heine P., Kegel B., Kohring K.)
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artykuł: Enzyme activities of purine metabolism in neurological disorders (Tozzi M. G., Pesi R., Camici M., Jacomelli G., Peruzzi L., Micheli V.)
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artykuł: AMPD1: ancient mutations provide insight into the pathogenesis of modern day disorders (Loh E., Oefner P., Holmes E.)
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artykuł: Diminished expression of adenosine kinase in diabetic rats (Sakowicz M., Pawelczyk T.)
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artykuł: 6-aryloxy-2-chloro- and 6-alkoxyaryl-2-chloropurines are potent inhibitors of E.coli purine nucleoside phosphorylase [PNP] (Bzowska A., Magnowska L., Kazimierczuk Z.)
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artykuł: A competitive template RT-PCR to measure mRNA encoding for folate metabolizing enzymes, such as thimidylate synthase, in leukemia and colon cancer (Peters G. J., Rots M. G., Noordhuis P., Mauritz R., Willey J. C., Demuth J. P., Van Zantwijk C. H., Pieters R., Jansen G.)
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artykuł: Kelley-Seegmiller syndrome due to a unique variant of hypoxanthine-guanine phosphoribosyltransferase: reduced affinity for 5-phosphoribosyl-1-pyrophosphate manifested only at low, physiological substrate concentrations (Zoref-Shani E., Feinstein S., Frishberg Y., Bromberg Y., Sperling O.)
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artykuł: Characteristic changes in erythrocyte nucleotides in haemolytic anaemia with basophilic stippling of differing aetiology (Laurence A., Duley J. A., Simmonds H. A., Layton M.)
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artykuł: Succinylpurinemic autism: possible side effects of D-ribose therapy (Salerno C., Celli M., Finocchiaro R., Matrunola M., D'Eufemia P., Giardini O.)
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artykuł: Collateral sensitivity to gemcitabine of P-GP and MRP overexpressing human non-small cell lung cancer [NSCLC] cell lines: a possible role of corticosteroids (Bergman A. M., Pinedo H. M., Loves W. J. P., Veerman G., Peters G. J.)
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artykuł: Role of 5'-nucleotidases [c-N-II and e-N-s] and AMP deaminase in the metabolism of AMP in the cytosol of rat brain. An experimental and theoretical approach (Sillero A., Torrecilla A., Marques A. E. P., Teixeira N. A., Atencia E. A., Sillero M. A. G.)
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artykuł: In vitro cytotoxicity of the tricyclic analogues of acyclovir (Wolun M., Ciesielski M., Goslinski T., Warchol J. B., Golankiewicz B.)
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artykuł: Pyridine nucleotides in erythrocytes and lymphocytes of HPRT deficient patients (Micheli V., Jacomelli G., Sestini S., Notarantonio L., Di Marcello F., Peruzzi L., Pompucci G.)
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artykuł: Specific and nonspecific enzymes involved in the catabolism of minor mono- and dinucleoside polyphosphates (Guranowski A.)
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artykuł: Deletion and point mutants of recombinant bovine 5'-nucleotidase (Allegrini S., Faedda A., Pesi R., Luculli F., Eriksson S., Tozzi M. G.)
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artykuł: High reactivity of anti-HIV nucleotide D4T with nucleoside diphosphate kinase at the molecular level (Schneider B., Biondi R., Sarfati R., Guerreiro C., Deville-Bonne D., Veron M.)
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artykuł: Amino acid 106 in human cytosolic thymidine kinase is a valine, and is important for the oligomerisation and enzymatic properties (Berenstein D., Christensen J. F., Frederiksen H., Kristensen T., Munch-Petersen B.)
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artykuł: Association of ecto-5'-nucleotidase activity and erbB-2 receptor function (Rosi F., Tabucchi A., Carlucci F., Marinello E., Cinci G., Zanoni L.)
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artykuł: Morphogenesis of B103 neuroblastoma and B103-4C its mutant derivative: modelling Lesch-Nyhan syndrome (Ma M. H. Y., Stacey N. C., Duley J. A., Connolly G. P.)
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artykuł: Defective adenylosuccinate lyase is inhibited by the lipid peroxidation product 4-hydroxy-2-nonenal (Salerno C., Siems W. G., Crifo C.)
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artykuł: Depletion of guanine nucleotides in human neuroblastoma cell lines (Agliano A. M., Gazzaniga P., Messina E., Micheli V., Spoto G., Giacomello A.)
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artykuł: Antibodies and nucleotide analogues: their effect on the allosteric response in the mammalian carbamoyl phosphate synthetase II [CPS II], the key reaction in pyrimidine biosynthesis (Carrey E. A., Zhu L.)
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artykuł: Genetic analysis of erythrocyte AMP deaminase deficiency (Ogasawara N., Yamada Y., Goto H.)
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artykuł: Enhanced adenosine production in human endothelium by inhibition of adenosine metabolism and nucleotide precursor supply (Smolenski R. T., Kalsi K. T., Gray C. C., Zych M., Kochan Z., Yacoub M. H.)
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artykuł: The role of adenosine in preconditioning (De Jong J. W., De Jonge R., Bradamante S.)
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artykuł: Metabolism and cytotoxic effects of 2-chloroadenine, the major catabolite of 2-chloro-2'-deoxyadenosine (Bontemps F., Delacauw A., Cardoen S., Van Den Neste E., Van Den Berghe G.)
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artykuł: Do subjects with mutation in muscle specific AMP deaminase gene have an enhanced blood flow response to sprint exercise ? (Norman B., Sabina R. L., Jansson E.)
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artykuł: Different responses for Ap5A and ATP in human cerebrocortical synaptic terminals (Pintor J., Diaz-Hernandez M., Gualix J., Gomez-Villafuertes R., Miras-Portugal T.)
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artykuł: Morphological abnormalities of HGPRT-deficient mouse N2a neuroblastoma: implications for neuronal development in Lesch Nyhan syndrome (Stacey N. C., Ma M. H. Y., Duley J. A., Connolly G. P.)
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artykuł: Catecholamine content of neuroblastoma: modelling Lesch-Nyhan syndrome [LNS] (Korenevsky A. V., Duley J. A., Connolly G. P.)
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artykuł: Indications for investigations of purine and pyrimidine disorders (Sebesta I., Krijt J., Kmoch S., Kumsta M., Stiburkova B.)
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artykuł: Thiopurine methyl transferase activity is correlated to azathioprine toxicity in patients with inflammatory bowell disease (Shobowale-Bakre E. M., Duley J., Hassan C., Ansari A., Reffitt D., Meenan J., Sanderson J. D.)
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artykuł: Purine and pyrimidine levels in cultured skin fibroblasts from control and Lesch-Nyhan patients (Hussain S. P., Duley J. A., Connolly G. P.)
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artykuł: Localization of adenosine deaminase [ADA] and purine nucleoside phosphorylase [PNP] in human hepatic and renal tissues - immunohistochemical method (Moriwaki Y., Yamamoto T., Yamakita J. I., Takahashi S., Tsutsumi Z., Higahino K.)
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artykuł: Several ligases and firefly luciferase catalyze the synthesis of dinucleoside polyphosphates (Sillero A., Sillero M. A. G.)
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artykuł: Abnormal intracellular signalling in skin fibroblasts from LNS patients and HGPRT-deficient neuroblastoma (Hussain S. P., Alexander N., Duley J. A., Connolly G. P.)
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artykuł: Is decreased renal uric acid excretion in familial hyperuricemia linked to 17q21 ? (Grassler J., Parpart B., Kuhlisch E., Spitzenberger F., Kopprasch S., Schroder H. E.)
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artykuł: Partial hypoxanthine - guanine phosphoribosyltransferase deficiency in young man (Kumsta M., Krijt J., Sebesta I.)
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artykuł: Expression and purification of murine dihydroorotate dehydrogenase and its inhibition by dichloroally-lawsone, redoxal, brequinar and leflunomide-A771726 (Knecht W., Ullrich A., Loffler M.)
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artykuł: An unexpected effect of 2-chloro-2'deoxyadenosine on DNA synthesis in EHEB cells (Cardoen S., Bontemps F., Van Den Neste E., Van Den Berghe G.)
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artykuł: Elevated succinylpurines in the cerebrospinal fluid of patient with fumarase deficiency (Krijt J., Zeman J., Kmoch S., Stratilova L., Hansikova H., Sebesta I.)
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artykuł: Characterisation of hypoxanthine-guanine phosphoribosyltransferase-deficient [HGPRT-] neuroblastoma: models for Lesch-Nyhan syndrome (Ma M. H. Y., Stacey N. C., Korenevsky A. V., Duley J. A., Connolly G. P.)
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artykuł: Isolation and characterization of AMP-selective 5'-nucleotidase from cytosol of pigeon breast muscle and brain (Tkacz K., Skladanowski A. C., Makarewicz W.)
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artykuł: Allogeneic bone marrow transplantation corrects the immunodeficiency in PNP deficiency but does not reverse the neurological abnormalities (Hallett R. J., Gaspar B., Duley J. A., Fairbanks L. D., Simmonds H. A.)
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artykuł: Differences in adenine incorporation between human and rat heart endothelium (Kalsi K. K., Zych M., Slominska E., Kochan Z., Yacoub M. H., Smolenski R. T.)
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artykuł: Cyclic nucleotide analogs as prospective drugs (Schwede F., Genieser H. G., Jastorff B.)
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artykuł: Role of ATP, dinucleoside polyphosphates and adenosine receptors in renal function (Angielski S.)
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artykuł: Ecto-nucleotidase activity of cultured rat superior cervical ganglia (Connolly G. P., Duley J. A.)
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artykuł: Nucleotide metabolism in an Italian APRT deficient patient (Micheli V., Jacomelli G., Barberi S., Burroni B., Di Marcello F., Notarantonio L., Peruzzi L., Mazzaferro S., Pompucci G.)
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artykuł: Effects of heat stress on metabolism of high-energy phosphates: comparison of normothermic and hypothermic ischemia (Jayakumar J., Smolenski R. T., Amrani M., Yacoub M. H.)
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artykuł: Leflunomide and methotrexate inhibit T-lymphocyte proliferation by different molecular mechanisms involving purine and pyrimidine de novo synthesis (Ruckemann K., Fairbanks L. D., Simmonds H. A.)
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artykuł: Influence of heat stress on myocardial metabolism and functional recovery after cardioplegic arrest: A P N.M.R. study (Jayakumar J., Smolenski R. T., Amrani M., Yacoub M. H.)
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artykuł: Adenosine and hypoxanthine inhibits neurite outgrowth from human brain cells (Korenevsky A. V., Duley J. A., Connolly G. P.)
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artykuł: Demonstration in living human cells that carbamoyl aspartate and carbamoyl phosphate accumulate when dihydro-orotate dehydrogenase is inhibited (Simmonds H. A., Ruckemann K., Fairbanks L. D., Carrey E. A.)
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artykuł: Human red blood cell thiopurine methyl transferase: HPLC assay for phenotype determination (Boulieu R., Gallant I., Sauviat M., Dervieux T.)
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artykuł: Decreased in vivo toxicity and enhanced cytotoxicity of FdUMP (Gmeiner W. H., Liu J., Talmadge J.)
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artykuł: Cytosolic purine 5'-nucleotidase from chicken heart: an isozyme of the liver enzyme as evidenced by northern blot analysis (Oka J.)
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artykuł: Methyl orange: a selective antagonist for pyrimidinoceptors (Connolly G. P.)
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artykuł: Nucleoside 5'-tetraphosphate hydrolase from human placenta (Pietrowska-Borek M., Szalata M., Guranowski A.)
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artykuł: Regulation of carbamoyl phosphate synthetase II [CAD] by MAP kinase; A new link to pyrimidine nucleotide synthesis ? (Graves L. M., Guy H. I., Kozlowski P., Dahlstrand E. N., Lazarowski E., Collins M., Earp H. S., Evans D. R.)
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artykuł: Deoxycytidine kinase transfection and upregulation of thymidine kinase 2 increased sensitivity to cytidine analogues in resistant cells (Van Der Wilt C. L., Loves W. J. P., Padron J., Talianidis I., Eriksson S., Peters G. J.)
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artykuł: Gemcitabine affects the detection of deoxyribonucleotides with a DNA polymerase elongation assay (Van Moorsel C. J. A., Smid K., Pinedo H. M., Peters G. J.)
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artykuł: Determination of nucleotides and its metabolic products in human saliva (Kochanska B., Smolenski R. T., Knap N.)
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artykuł: A mutation in the 5'UTR of the ADSL gene in a patient with adenylosuccinate lyase deficiency (Marie S., Race V., Nassogne M. C., Vincent M. F., Van Den Berghe G.)
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artykuł: Control of energy metabolism in the heart and endothelial cells (Schrader J., Decking U. K. M., Stumpe T., Culic O.)
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artykuł: Exclusion of four candidate kidney disease loci by linkage analysis in familial juvenile hyperuricaemic nephropathy [FJHN] (Greener M., Marinaki A. M., Town M. M., Moro F., Simmonds H. A., Cameron J. S., Duley J. A., Mathew C.)
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artykuł: Cytotoxicity of cyclopentenyl cytosine towards neuroblastoma cell line cells (Bierau J., Van Gennip A. H., Van Kuilenburg A. B. P.)
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artykuł: Capillary electrophoresis for diagnosing purine inherited disorders - two complementary approaches (Adam T., Friedecky D., Fairbanks L. D., Bartak P., Sevcik J.)
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artykuł: Purine nucleosides metabolism in blood fractions from patients with Graves' or Hashimoto diseases (Fabianowska-Majewska K., Karbownik M., Zasada K., Lewinski A., Wyczechowska D.)
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artykuł: Effect of heat stress on mitochondrial adenine nucleotide pools in rat myocardium (Sammut I. A., Jayakumar J., Yacoub M. H., Smolenski R. T.)
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artykuł: Pitfalls in the diagnosis of patients with a dihydropyrimidine dehydrogenase deficiency in blood cells (Van Kuilenburg A. B. P., Van Lenthe H., Van Gennip A. H.)
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artykuł: Inducible overexpression of cytosolic 5'nucleotidases in mammalian cells (Gazziola C., Moras M., Ferraro P., Rampazzo C., Gallinaro L., Reichard P., Bianchi V.)
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artykuł: Urinary excretion of some methylated purine bases in healty subjects (Di Pietro M. C., Liso G., D'Ercole M., Porcelli B., Leoncini R., Mannello E., Vannoni D.)
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artykuł: The experimental and theoretical study of 6-thioguanine and their derivatives (Rubin Y., Leszczynski J.)
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artykuł: The effect of different nucleoside-5'-thiosulphates on the salvage of deoxypyrimidine nucleosides in human lymphocytes (Szikla K., Kazimierczuk Z., Virga S., Staub M.)
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artykuł: Scientific basis for effective combination chemotherapy (Peters G. J.)
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artykuł: Demonstration of dihydroorotate dehydrogenase manifestation in human and bovine spermatozoa (Loffler M., Dietz C., Hinsch E., Grein K., Edelmann P., Schneider V.)
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artykuł: Cyclopentenyl cytosine inhibits CTP synthetase in pediatric acute non-lymphocytic leukemia (Verschuur A. C., Van Gennip A. H., Leen R., Voute P. A., Van Kuilenburg A. B. P.)
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artykuł: Human diadenosine triphosphate hydrolase: preliminary characterization and comparison with the human tumor suppressor Fhit protein (Rotllan P., Asensio A. C., Oaknin S.)
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artykuł: Towards an understanding of the functional significance for N-terminal domain divergence in human AMP deaminase isoform (Sabina R. L., Mahnke-Zizelman D. K.)
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artykuł: Oxidative stress and ischemic damage in patients undergoing coronary artery by-pass surgery (Carlucci F., Biagioli B., Maccherini M., Sani G., Lisi G., Marinello E., Tabucchi A.)
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artykuł: Changes in membrane phospholipid biosynthesis induced by chloropromasine and nucleoside analogues: its therapeutic consequences (Staub M., Sumeg R., Sasvari-Szekely M., Simmonds H. A.)
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artykuł: HPLC-determination of thiopurine methyltransferase [TPMT]-activity (Brouwer C., Keizer-Garritsen J. J., De Abreu R. A., Bokkerink J. P. M., Ter Riet P. G. J. H., Trijbels J. M. F.)
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artykuł: Pyridine nucleotide concentration and activity of related enzymes in human lymphocytes (Sestini S., Jacomelli G., Pescaglini M., Micheli V., Pompucci G.)
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artykuł: Effect of amino acids on the plasma concentrations and urinary excretion of uric acid and uridine (Yamamoto T., Moriwaki Y., Takahashi S., Tsutsumi Z., Yamakita J. I., Higashino K.)
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artykuł: Purine nucleoside phosphorylases: properties, functions, and chemotherapeutic applications (Shugar D.)
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artykuł: Modulation of human deoxycytidine kinase activity as a response to different cellular stresses (Sasvari-Szekely M., Csapo Z., Spasokukockaja T., Talianidis I., Staub M.)
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artykuł: When [2-3H]inositol is added to intra-abdominal Ehrlich tumour cell growths in mice, the ATP and GTP of the harvested cells are stably labelled with 3H in both ribose and base (Christensen S., Klenow H., Overgaard-Hansen K.)
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artykuł: Regulatory mechanisms of smooth muscle AMP-deaminase (Kaletha K., Szymanska G., Nagel-Starczynowska G.)
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artykuł: The activity of dihydropyrimidine dehydrogenase and mRNA expression in human blood cells (Van Kuilenburg A. B. P., Vreken P., Van Lenthe H., Meinsma R., Van Gennip A. H.)
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artykuł: Ecto-5'-nucleotidase activity and CD73 expression in patients at different stages of the B-cell chronic lymphocytic leukemia (Rosi F., Marotta G., Raspadori D., Bellisai B., Marinello E., Carlucci F., Tabucchi A.)
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artykuł: Ecto-5'-nucleotidase activity is reduced in the presence of TNF-alpha in human endothelial cells (Kalsi K. K., Lawson C., McCormack A., Yacoub M. H., Smolenski R. T.)
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artykuł: Cerebrospinal fluid hipoxanthine, xanthine and uric acid concentrations in different inherited metabolic diseases [IMD] (Larovere L., Latini A., Coronel C. E., De Kremer R. D.)
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artykuł: Novel adenosine deaminase inhibitors and their cytoprotective effects (Barankiewicz J.)
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artykuł: Is there a rescue - scheme for the chemotherapy with gemcitabine ? (Wosegien F., Graeve T.)
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artykuł: Enhanced adhesion of neuroblastoma models of Lesch-Nyhan syndrome [LNS] and human skin fibroblast from LNS patients (Stacey N. C., Ma M. H. Y., Duley J. A., Connolly G. P.)
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artykuł: Reduced purine 5'-nucleotidase activity in lymhocytes of patients with systemic lupus erythematosus (Stolk J. N., Boerbooms A., De Abreu R. A., De Koning D., Van De Putte L.)
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artykuł: Gemcitabine induced cell cycle disturbances and apoptosis in lung cancer cell lines; Basis for combination therapy with topotecan and taxol (Kroep J. R., Giaccone G., Tolis C., Ferreira C. G., Pinedo H. M., Peters G. J.)
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artykuł: Methanetrisphosphonate and its adenine nucleotide derivatives as inhibitors of human and plant diadenosine tetraphosphate hydrolases (Maksel D., Gayler K., Liu X., Blackburn M., McLennan A. G., Guranowski A.)
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artykuł: Combination therapy in childhood leukemia, in vitro studies of thiopurines and inhibitors of purine metabolisms on apoptosis (Trueworthy R., De Abreu R., Vogels-Mentink T., Lambooy L. M.)
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artykuł: Molecular studies of 5'nucleotidases: past achievements and future potential (Newby A. C.)
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artykuł: Recombinant expression of a multisubstrate deoxynucleoside kinase from Drosophila melanogaster (Knecht W., Lenz C., Sondergaard L., Piskur J., Munch-Petersen B.)
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artykuł: Relation between fractional excretion of uric acid and fasting serum glucose in male children (Messina E., Giacomello A.)
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artykuł: Therapeutic application of mycophenolic acid in autoimmune diseases and transplantation medicine (Muller M. M., Heinschink A., Griesmacher A., Neumann I.)
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artykuł: Rescue of sympathetic neurons from NGF-withdrawal apoptosis by adenosine (Wakade A. R., Wakade T. D., Przywara D. A.)
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artykuł: Abnormal purine and pyrimidine nucleotide content in primary astroglia cultures from HGPRT - deficient transgenic mice (Pelled D., Sperling O., Zoref-Shani E.)
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artykuł: Familial juvenile hyperuricaemic nephropathy [FJHN] in three Czech families (Stiburkova B., Pospisilova E., Paterova T., Krijt J., Kumsta M., Sebesta I., Kmoch S.)
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artykuł: Human liver AMP-deaminase - regulatory properties of the enzyme (Kaletha K., Dutka P., Nagel-Starczynowska G.)
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artykuł: A case of classical xanthinuria type 1 determined by the simplified allopurinol loading test-new mutation in xanthine dehydrogenase gene (Ichida K., Takahashi K., Matsuda O., Kimura H., Hosoya T.)
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artykuł: Enantiospecificity of human deoxycytidine kinase [dCK] and thymidine kinases [TK1 and TK2] towards 3'-branched homologues of 2'-deoxynucleosides (Banrowski M., Krawiec K., Johansson N. G., Shugar D., Kierdaszuk B.)
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artykuł: Capillary electrophoresis as a tool for determining the level of orotic acid and uracil in patients with urea cycle defects (Salerno C., D'Eufemia P., Celli M., Finocchiaro R., Crifo C., Giardini O.)
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artykuł: Transformation of dimeric low-affinity form of human thymidine kinase [TK1] to the tetrameric high-affinity form [ATP-form] (Zuberek J., Munch-Petersen B., Shugar D., Kierdaszuk B.)
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artykuł: Deoxycytidine kinase and deaminase activities in human liver and liver metastasis (Kroep J. R., Pinedo H. M., Voorn D. A., Loves W. J. P., Van Der Wilt C. L., Van Groeningen C. J., Peters G. J.)
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artykuł: Metabolic properties of purine and pyrimidine nucleoside analogues, active against HIV (Balzarini J.)
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