Warianty tytułu
Języki publikacji
Abstrakty
Two human clinical studies were performed. One was an open-label non-controlled study involving 30 healthy female subjects for 8 weeks. Significant improvements were observed by combining 6 mg per day oral supplementation and 2 ml (78.9 μM solution) per day topical application of astaxanthin. Astaxanthin derived from the microalgae, Haematococcus pluvialis showed improvements in skin wrinkle (crow's feet at week-8), age spot size (cheek at week-8), elasticity (crow's feet at week-8), skin texture (cheek at week-4), moisture content of corneocyte layer (cheek in 10 dry skin subjects at week-8) and corneocyte condition (cheek at week-8). It may suggest that astaxanthin derived from H. pluvialis can improve skin condition in all layers such as corneocyte layer, epidermis, basal layer and dermis by combining oral supplementation and topical treatment. Another was a randomized double-blind placebo controlled study involving 36 healthy male subjects for 6 weeks. Crow's feet wrinkle and elasticity; and transepidermal water loss (TEWL) were improved after 6 mg of astaxanthin (the same as former study) daily supplementation. Moisture content and sebum oil level at the cheek zone showed strong tendencies for improvement. These results suggest that astaxanthin derived from Haematococcus pluvialis may improve the skin condition in not only in women but also in men.
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Opis fizyczny
p.43-47,fig.,ref.
Twórcy
autor
- Fuji Chemical Industry Co. Ltd., Kamiichi, Toyama, Japan
autor
autor
autor
Bibliografia
- Arakane K (2002) Superior skin protection via astaxanthin. Carotenoid Science 5: 21-24.
- Goto S, Kogure K, Abe K, Kimata K, Kitahama K, Yamashita E, Terada H (2001) Efficient radical trapping at the surface and inside the phospholipid membrane is responsible for highly potent antioxidative activity of the carotenoid astaxanthin. Biochim Biophys Acta 1512: 251-258.
- Kuhn R, Sorensen NA (1938) The coloring matters of the lobster (Astacus gammarus L.). Z Angew Chem 51: 465-466.
- Lee SJ, Bai SK, Lee KS, Namkoong S, Na HJ, Ha KS, Han JA, Yim SV, Chang K, Kwon YG, Lee SK, Kim YM (2003) Astaxanthin inhibits nitric oxide production and inflammatory gene expression by suppressing IκB kinase-dependent NF-κB activation. Mol Cells 16: 97-105.
- Martin HD, Ruck C, Schmidt M, Sell S, Beutner S, Mayer B, Walsh R (1999) Chemistry of carotenoid oxidation and free radical reactions. Pure Appl Chem 71: 2253-2262.
- Matsuno T (1991) Xanthophylls as precursors of retinoids. Pure Appl Chem 63: 81-88.
- Miki W (1991) Biological functions and activities of animal carotenoids. Pure Appl Chem 63: 141-146.
- Seki T, Sueki H, Kono H, Suganuma K, Yamashita E (2001) Effects of astaxanthin from Haematococcus pluvialis on human skin-patch test; skin repeated application test; effect on wrinkle reduction. Fragrance J 12: 98-103.
- Task Force Committee for Evaluation of Anti-aging Function (2007) Guideline for evaluation of anti-wrinkle products in "Guidelines for evaluation of cosmetic functions". J Jpn Cosmet Sci Soc 31: 411-431.
- Tominaga K, Hongo N, Karato M, Yamashita E (2009) Protective effects of astaxanthin against singlet oxygen induced damage in human dermal fibroblasts in vitro. Food Style 21 13: 84-86.
- Yamashita E (1995) Suppression of post-UVB hyperpigmentation by topical astaxanthin from krill. Fragrance J 14: 180-185.
- Yamashita E (2002) Cosmetic benefit of dietary supplements including astaxanthin and tocotrienol on human skin. Food Style 21 6: 112-117.
- Yamashita E (2006) The effects of a dietary supplement containing astaxanthin on skin condition. Carotenoid Science 10: 91-95.
- Yuan JP, Peng J, Yin K, Wang JH (2010) Potential health-promoting effects of astaxanthin: a high-value carotenoid mostly from microalgae. Mol Nutr Food Res 55: 150-165
Uwagi
PL
Rekord w opracowaniu.
Typ dokumentu
Bibliografia
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