Selected parameters of immune response in pregnant sows vaccinated against Trueperella pyogenes

• Autorzy: Kostro K. , Lisiecka U. , Zmuda A. , Niemczuk K. , Stojecki K. , Taszkun I.
• Języki publikacji: EN

Abstrakty

EN

Expression of CD4, CD8, and CD25 surface markers on T lymphocytes and levels of IFNγ, IL-10, and TNF-α in colostrum and milk were determined in sows vaccinated against Trueperella pyogenes in the final stage of pregnancy. The autovaccine, prepared from Trueperella pyogenes, administered twice to pregnant sows six and three weeks before the anticipated delivery significantly increased the percentages of TCD4+, TCD8+, and TCD25+ as well as levels of IFNγ, TNF-α, and IL-10 in colostrum and milk. The enhanced immune potential of colostrum effectively protected the piglets against T. pyogenes infections during weaning and thus reduced the economic losses on the particular farm concerned, where T. pyogenes infections occur endemically. Knowledge of the profile of cellular and humoral immune response in colostrum and milk of vaccinated sows will enable the design of a T. pyogenes infection prophylactic programme for suckling pigs and weaners, which are most susceptible to infections.

• Wydawca: -
• Czasopismo: Bulletin of the Veterinary Institute in Puławy
• Rocznik: 2014
• Tom: 58
• Numer: 1
• Opis fizyczny: p.17-21,fig.,ref.

Twórcy

autor

Kostro K.

• Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-612 Lublin, Poland

autor

Lisiecka U.

• Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-612 Lublin, Poland

autor

Zmuda A.

• Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-612 Lublin, Poland

autor

Niemczuk K.

• National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Stojecki K.

• Department of Parasitology and Invasive Diseases, National Veterinary Research Institute, 24-100 Pulawy, Poland

autor

Taszkun I.

• Department of Epizootiology and Clinic of Infectious Diseases, Faculty of Veterinary Medicine, University of Life Sciences in Lublin, 20-612 Lublin, Poland

Bibliografia

• 1. Billington S.J., Jost B.H., Cuevas W.A., Bright K.R., Songer J.G.: The Arcanobacterium (Actinomyces) pyogenes hemolysin, pyolysin, is a novel member of the thiol-activated cytolysin family. J Bacterid 1997, 179, 6100- 6106.
• 2. Dean-Nystrom E.A., Gransheroff L.J., Mills M., Moon H.W., O'Brien A.D.: Vaccination of pregnant dams with intimin O157 protects suckling piglets from Escherichia coli O157:H7 infection. Infect Immun 2002, 70, 2414-2418.
• 3. Esmay P.A., Billington S.J., Malen A., Link M.A., Songer J., Jost B.H.: The Arcanobacterium pyogenes collagen-binding protein, cbpA promotes adhesion to host cells. Infect Immun 2003, 71, 4368-4374.
• 4. Jost B.H., Billington S.J : Arcanobacterium pyogenes: molecular pathogenesis of an animal opportunist. Antonie van Leeuwenhoek 2005, 88, 87-102.
• 5. Krakowski L., Krzyżanowski J., Wrona Z., Kostro K., Siwicki A.K.: The influence of nonspecific immunostimulation of pregnant sows on the immunological value of colostrum. Vet Immunol Immunopathol 2002, 87, 89-95.
• 6. Milanov D., Petrović J., Kapetanov M., Suvajdzić L.: Arcanobacterium pyogenes - virulence factors, importance in mastitis etiology and therapeutic possibilities. Veterinarski Glasnik 2011, 65, 235-246.
• 7. Nechvatalova K., Kudlackova H., Leva L., Babickova K., Faldyna M.: Transfer of humoral and cell-mediated immunity via colostrum in pigs. Vet Immunol Immunopathol 2011, 142, 95-100.
• 8. Nguyen T.V., Yuan L., Azevedo M.S., Jeong K.I., Gonzalez A.M., Saif L.J.: Transfer of maternal cytokines to suckling piglets: in viro and in vitro models with implications for immunomodulation of neonatal immunity. Vet Immunol Immunopathol 2007, 117, 236-248.
• 9. Pomorska-Mól M., Markowska-Daniel I., Bednarek D.: Flow cytometric analysis of leukocytes in porcine mammary secretions. Bull Vet Inst 2010, 54, 188-192.
• 10. Salmon H., Berri M., Gerdts V., Meurens F.: Humoral and cellular factors of maternal immunity in swine. Dev Comp Immunol 2009, 33, 384-393.
• 11. Olbegi-Mohyla H.. Hijazin M., Alber J., LämmLer C., Hassan A.A., Abdulmawjood A., Prenger Berninghoff E., Weiß R., Zschöck M.: Identification of Arcanobacterium pyogenes isolated by post mortem examinations of a bearded dragon and a gecko by phenotypic and genotypie properties. J Vet Sci 2010, 11, 265-267.
• 12. Wuryastuti H.J., Stowe H.D., Bull R.W., Miller E.R.: Effects of vitamin E and selenium on immune responses of peripheral blood, colostrum, and milk leukocytes of sows. J Anim Sci 1993, 71, 2464-2472.