Czasopismo
Tytuł artykułu
Warianty tytułu
Języki publikacji
Abstrakty
A multiresidue method (LC-MS/MS) for determination of wide range of anthelmintics was developed. The method covered benzimidazoles: albendazole (and metabolites), cambendazole, fenbendazol (and metabolites), flubendazole (and metabolites), mebendazole (and metabolites), oxibendazole, thiabendazole (and metabolites), triclabendazole (and metabolites); macrocyclic lactones: abamectin, doramectin, emamectin, eprinomectin, ivermectin, moxidectin; salicylanilides: closantel, ioxynil, nitroxynil, oxyclosamide, niclosamide, rafoxanid and others: clorsulon, derquantel, imidocarb, monepantel (and metabolites), morantel, praziquantel, and pyrantel. The method was used to examine the potential presence of anthelmintics in goat and sheep milk and dairy products from the Polish market. A total of 120 samples of milk, yoghurt, cottage cheese, cream cheese, and curd were analysed. None of the samples were found positive above CCa (1-10 µg/kg) except for one cottage cheese in which traces of albendazole sulfone were detected (5.2 µg/kg) and confirmed. The results of the study showed negligible anthelmintic residues in the goat and sheep milk and dairy products and confirm their good quality.
Wydawca
Rocznik
Tom
Numer
Opis fizyczny
p.515-518,fig.,ref.
Twórcy
autor
- Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
- Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland
autor
- Department of Food Hygiene, National Veterinary Research Institute, 24-100 Pulawy, Poland
- Department of Pharmacology and Toxicology, National Veterinary Research Institute, 24-100 Pulawy, Poland
Bibliografia
- 1. Aguilera-Luiz M.M., Vidal J.L.M., Romero-González R., Frenich A.G.: Multi-residue determination of veterinary drugs in milk by ultra-high-pressure liquid chromatography-tandem mass spectrometry. J Chromatogr A 2008, 1205, 10-16.
- 2. Anastasio A., Veneziano V., Capurro E., Rinaldi L., Cortesi M.L., Rubino R., Danaher M., Cringoli G.: Fate of eprinomectin in goat milk and cheeses with different ripening times following pour-on administration. J Food Prot 2005, 68, 1097-1101.
- 3. Chen D., Tao Y., Liu Z., Liu Z., Huang L., Wang Y., Yuan Z.: Development of a high-performance liquid chromatography method to monitor the residues of benzimidazoles in bovine milk. J Chromatogr B Analyt Technol Biomed Life Sci 2010, 878, 2928-2932.
- 4. Commission Decision 2002/657/EC of August 2002 implementing Council Directive 96/23/EC concerning the performance of analytical methods and the interpretation of results. Off J Eur Commun 2002, L 221, 8-36.
- 5. European Food Safety Authority (2012) Report for 2010 on the results from the monitoring of veterinary medicinal product residues and other substances in live animals and animal products, http://www.efsa.europa.eu/fr/supporting/pub/212e.
- 6. European Food Safety Authority, Scientific Opinion: Scientific Opinion on the suitability of goat milk protein as a source of protein in infant formulae and in follow-on formulae. EFSA J 2012, 10, 2603-2610.
- 7. Fleming S.A., Craig T., Kaplan R.M., Miller J.E., Navarre Ch., Rongs M.: Anthelmintic resistance of gastrointestinal parasites in small ruminants. J Vet Intern Med 2006, 20, 4350-4444.
- 8. Fletouris D.J., Botsoglou N.A., Psomas I.E., Mantis A.I.: Albendazole-related drug residues in milk and their fate during cheesemaking, ripening, and storage. J Food Prot 1998, 61, 1484-1488.
- 9. Furlani R.P.Z., Dias F.F.G., Nogueira P.M., Gomes F.M.L., Tfouni S.A.V., Camargo M.C.R.: Occurrence of macrocyclic lactones in milk and yogurt from Brazilian market. Food Control 2014, 48, 43-47.
- 10. Gómez Pérez M.L., Romero-González R., Martínez Vidal J.L., Garrido Frenich A.: Analysis of veterinary drug residues in cheese by ultra-high-performance LC coupled to triple quadrupole MS/MS. J Sep Sci 2013, 36, 1223-1230.
- 11. Imperiale F.A., Busetti M.R., Suárez V.H., Lanusse C.E.: Milk excretion of ivermectin and moxidectin in dairy sheep: assessment of drug residues during cheese elaboration and ripening period. J Agric Food Chem 2004, 52, 6205-6211.
- 12. Imperiale F A., Mottier L., Sallovitz J.M., Lifschitz A.L., Lanusse C.E.: Disposition of doramectin milk residues in lactating dairy sheep. J Agrie Food Chem 2003, 51, 3185-3190.
- 13. Imperiale F., Pis A., Sallovitz J., Lisfchitz A., Busetti M., Suárez V., Lanusse C.: Pattern of eprinomectin milk excretion in dairy sheep unaffected by lactation stage: comparative residual profiles in dairy products. J Food Prot 2006, 69, 2424-2429.
- 14. Jedziniak P., Olejnik M., Rola J., Szprengier Juszkiewicz T.: Determination of anthelmintic residues in dairy products. Food Addit Contamin 2015 (in press).
- 15. Kinsella B., Byrne P., Cantwell H., Mccormack M., Furey A., Danaher M.: Determination of the new anthelmintic monepantel and its sulfone metabolite in milk and muscle using a UHPLC- MS/MS and QuEChERS method. J Chromatogr B Analyt Technol Biomed Life Sci 2011, 879, 3707-3713.
- 16. Tsiboukis D., Sazakli E., Jelastopulu E., Leotsinidis M.: Anthelmintics residues in raw milk. Assessing intake by a children population. Pol J Vet Sci 2013, 16, 85-91.
- 17. Whelan M., Chirollo C., Furey A., Cortesi M.L., Anastasio A, Danaher M.: Investigation of the persistence of levamisole and oxyclozanide in milk and fate in cheese. J Agrie Food Chem 2010, 58, 12204-12209.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-bb7a0b93-d60d-4dd3-ba10-0308bfe211b4