Warianty tytułu
Possibilities of applying lactoferrin as an immunostimulant in fish and crustacean farming
Języki publikacji
Abstrakty
Lactoferrin (LF) is an iron-binding protein from the transferrin family present in mucosal secretions, several organs, secondary granules of neutrophils and the serum of mammals. Many biological functions have been attributed to lactoferrin, including immunomodulatory and anti-inflammatory properties. Although the presence of LF in fish is unknown, it has similar effects in fish as in mammals. In the majority of the investigated fish species LF promoted proliferative response of lymphocytes, modulated macrophage functions or increased phagocytosis and respiratory burst of fish leukocytes in vitro. Administration of LF reduced the mortality of fish challenged with pathogenic bacteria and viruses, and enhanced the resistance of fish to parasitic infections. Moreover LF treatment reduced the stress response of aquatic organisms cultured under deteriorating conditions. As a natural protein LF shows very low toxicity, high biocompatibility and biodegradability, and is considered safe for the environment and consumer health as well. Although LF had no effect on the immune system of several fish species, its use as an immunostimulant in aquaculture is still a promising area.
Słowa kluczowe
Wydawca
Czasopismo
Rocznik
Tom
Numer
Strony
95-98
Opis fizyczny
s.95-98,bibliogr.
Twórcy
autor
- Uniwersytet Warminsko-Mazurski w Olsztynie, ul.Oczapowskiego 13, 10-719 Olsztyn
autor
autor
Bibliografia
- 1.Bachere E.: Shrimp immunity and disease control. Aquaculture 2000, 191, 3-11.
- 2.Brock J.: Lactoferrin: a multifunctional immunoregulatory protein? Immunology Today 1995, 16, 9, 417-419.
- 3.Cecchini S., Caputo A. R., Mecca F.: Evaluation of in vitro endocytosis and antibody synthesis by rainbow trout head kidney cells treated with bovine lactoferrin. J. Fish Biol. 2005, 66, 609-617.
- 4.Chand R. K., Sahoo P. K., Kumari J., Pillai B. R., Mishra B. K.: Dietary administration of bovine lactoferrin influences the immune ability of the giant freshwater prawn Macrobrachium rosenbergii (de Man) and its resistance against Aeromonas hydrophila infection and nitrite stress. Fish Shellfish Immunol. 2006, 21, 119-129.
- 5.Esteban M. A., Rodriguez A., Cuesta A., Meseguer J.: Effects of lactoferrin on non-specific immune responses of gilthead seabream (Sparus auratus L.). Fish Shellfish Immunol. 2005, 18, 109-124.
- 6.Farnaud S., Evans R. W.: Lactoferrin - a multifunctional protein with antimicrobial properties. Mol. Immunol. 2003, 40, 395-405.
- 7.Kakuta I.: Reduction of stress response in carp, Cyprinus carpio L., held under deteriorating environmental conditions, by oral administration of bovine lactoferrin. J. Fish Dis. 1998, 21, 161-167.
- 8.Kamilya D., Ghosh D., Bandyopadhyay S., Mal. B. C., Maiti T. K.: In vitro effects of bovine lactoferrin, mushroom glucan and Abrus agglutinin on Indian major carp, catla (Catla catla) head kidney leukocytes. Aquaculture 2006, 253, 130-139.
- 9.Kamilya D., Maiti T. K., Joardar S. N., Mal B. C.: Adjuvant effect of mushroom glucan and bovine lactoferrin upon Aeromonas hydrophila vaccination in catla, Catla catla (Hamilton). J. Fish Dis. 2006, 29, 331-337.
- 10.Kumari J., Sahoo P. K.: Non-specific immune response of healthy and immunocompromised Asian catfish (Clarias batrachus) to several immunostimulants. Aquaculture 2006, 255, 133-141.
- 11.Kumari J., Swain T., Sahoo P. K.: Dietary bovine lactoferrin induces changes in immunity level and disease resistance in Asian catfish Clarias batrachus. Vet. Immunol. Immunopathol. 2003, 94, 1-9.
- 12.Lygren B., Sveier H., Hjeltnes B., Waagbo R.: Examination of the immunomodulatory properties ant the effect of disease resistance of dietary bovine lactoferrin and vitamin C fed to Atlantic salmon (Salmo salar) for a short-time period. Fish Shellfish Immunol. 1999, 9, 95-107.
- 13.Magnadottir B.: Innate immunity of fish (overview). Fish Shellfish Immunol. 2006, 20, 137-151.
- 14.Ren T., Koshio S., Ishikawa M., Yokoyama S., Micheal F. R., Uyan O., Tung H. T.: Influence of dietary vitamin C and bovine lactoferrin on blood chemistry and non-specific immune responses of Japanese eel, Anguilla japonica. Aquaculture 2007, 267, 31-37.
- 15.Sakai M.: Current research status of fish immunostimulants. Aquaculture 1999, 172, 63-92.
- 16.Sakai M., Kobayashi M., Yoshida T.: Activation of rainbow trout, Oncorhynchus mykiss, phagocytic cells by administration of bovine lactoferrin. Comp. Biochem. Physiol. 1995, 110B, 755-759.
- 17.Sakai M., Otubo T., Atsuta S., Kobayashi M.: Enhacement of resistance to bacterial infection In rainbow trout, Oncorhynchus mykiss (Walbaum), by oral administration of bovine lactoferrin. J. Fish Dis. 1993, 16, 239-247.
- 18.Smith V. J., Brown J. H., Hauton C.: Immunostimulation in crustaceans: does it really protect against infection? Fish Shellfish Immunol. 2003, 15, 71-90.
- 19.Steijns J. M.: Milk ingredients as nutraceuticals. Society of Dairy Technology, 2001, 54, 3, 81-88.
- 20.Tomita M., Wakabayashi H., Yamauchi K., Teraguchi S., Hayasawa H.: Bovine lactoferrin and lactoferricin derived from milk: production and applications. Biochem. Cell Biol. 2002, 80, 109-112.
- 21.Weifeng M., Yaping W., Wenbo W., Bo W., Jianxin F., Zuoyan Z.: Enhanced resistance to Aeromonas hydrophila infection and enhanced phagocytic activities in human lactoferrin-transgenic grass carp (Ctenopharyngodon idellus). Aquaculture 2004, 242, 93-103.
- 22.Welker T. L., Lim C., Yildirim-Aksoy M., Klesius P. H.: Growth, immune function, and disease and stress resistance of juvenile Nile tilapia (Oreochromis niloticus) fed graded levels of bovine lactoferrin. Aquaculture 2007, 262, 156-162.
- 23.Yokoyama S., Koshio S., Takakura N., Oshida K., Ishikawa M., Gallardo-Cigarroa F. J., Catacutan M. R., Teshima S.: Effect of dietary bovine lactoferrin on growth response, tolerance to air exposure and low salinity stress conditions in orange spotted grouper Epinephelus coioides. Aquaculture 2006, 255, 507-513.
- 24.Yokoyama S., Koshio S., Takakura N., Oshida K., Ishikawa M., Gallardo-Cigarroa F. J., Teshima S.: Dietary bovine lactoferrin enhances tolerance to high temperature stress in Japanese flounder Paralichthys olivaceus. Aquaculture 2005, 249, 367-373.
- 25.Zhong J., Wang Y., Zhu Z.: Introduction of the human lactoferrin gene into Grass carp (Ctenopharyngodon idellus) to increase resistance against GCH virus. Aquaculture 2002, 214, 93-101.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-article-fa8c0a2e-5ceb-432c-a391-c33a65720881