Aktualne poglady na budowe, funkcjonowanie i znaczenie receptorow glutaminianergicznych typu NMDA

• Autorzy: Kania B F , Cieciera M.

Warianty tytułu

EN

Current views on the structure, molecular function and role of the glutamate receptors NMDA

• Języki publikacji: PL

Abstrakty

EN

The paper reviews the terminology, molecular activity and role of the NMDA glutamate receptors. As excitatory aminoacid receptors these receptors are generally classified as ionotropic (NMDA, AMPA, KA) and metabotropic depending (mGluR₁₋₈) on whether they form ion channels or are coupled to G-proteins, respectively. Recent investigations indicated the essential role of the NMDA receptors in the nociceptive processus modulation. Recent progress has been made in the development of specific antagonists - such as MK-801, araxines, mementine, DL-AP-3, and others - for these receptors, and can siginicantly facilitate prophilaxy and therapy in different types of pain.

Słowa kluczowe

PL

dzialanie; fizjologia zwierzat; receptory NMDA; antagonisci receptorow NMDA; budowa

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2007
• Tom: 63
• Numer: 08
• Strony: 896-899
• Opis fizyczny: s.896-899,rys.,bibliogr.

Twórcy

autor

Kania B F

• Szkola Glowna Gospodarstwa Wiejskiego, ul.Nowoursynowska 159, 02-776 Warszawa

autor

Cieciera M.

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