Some aspects of oligoribonucleotides synthesis via the H-phosphonate approach

Stawinski, J; Kraszewski, A.

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Artykuł - szczegóły

Czasopismo

Acta Biochimica Polonica

1998 | 45 | 4 |

Tytuł artykułu

Some aspects of oligoribonucleotides synthesis via the H-phosphonate approach

Autorzy

Stawinski J. , Kraszewski A.

Warianty tytułu

Języki publikacji

Abstrakty

This review gives a short account of selected aspects of oligoribonucleotide synthesis via the H-phosphonate method. It includes: (i) recent methods for the preparation of suitably protected ribonucleoside 3'-H-phosphonates (the phosphonylation step), (ii) some chemical and stereochemical features of the formation of H-phosphonate internucleosidic linkages, and (iii) stereoselective synthesis of oligoribonucleoside phosphorothioates using chemo-enzymatic approach.

Słowa kluczowe

RNA stereoselective synthesis H-phosphonate method oligoribonucleotide synthesis oligonucleotide analogue

Wydawca

Czasopismo

Acta Biochimica Polonica

Rocznik

1998

Tom

Numer

Opis fizyczny

p.907-915,fig.

Twórcy

autor

Stawinski J.

Stockholm University, Stockholm, Sweden

autor

Kraszewski A.

Bibliografia

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Bibliografia

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