Effect of anthocyanins on selected biochemical parameters in rats exposed to cadmium

• Autorzy: Kowalczyk E. , Kopff A. , Fijalkowski P. , Kopff M. , Niedworok J. , Blaszczyk J. , Kedziora J. , Tyslerowicz P.
• Języki publikacji: EN

Abstrakty

EN

Cadmium is a dangerous occupational and environmental toxin. It accumulates in the human organism mainly in liver and kidneys. Cadmium half-life is about 10 years, so the symptoms of cadmium intoxication may occur several years after the exposure. Until now in treating intoxication with this metal chelating compounds have been used, burdened with numerous undesirable symptoms. In our investigations antho- cyanins from Aronia melanocarpa were used to reduce the harmful results caused by cadmium. Administering anthocyanins with cadmium chloride resulted in a statisti­cally significant decrease of aspartate aminotransferase (AST) and alanine amino­transferase (ALT) activity, concentration of bilirubin and urea in blood serum and de­creased cadmium cumulation in liver and kidneys in relation to animals receiving cadmium chloride only.

Słowa kluczowe

EN

human organism; alanine aminotransferase; blood serum; environmental toxin; cadmium chloride; rat; Aronia melanocarpa; urea; bilirubin; occupational toxin; aspartate aminotransferase; cadmium cumulation; cadmium; kidney; liver; biochemical parameter; anhocyanin

• Wydawca: -
• Czasopismo: Acta Biochimica Polonica
• Rocznik: 2003
• Tom: 50
• Numer: 2
• Opis fizyczny: p.543-548

Twórcy

autor

Kowalczyk E.

• Medical University, Plac J.Hallera 1, 90-647 Lodz, Poland

autor

Kopff A.

autor

Fijalkowski P.

autor

Kopff M.

autor

Niedworok J.

autor

Blaszczyk J.

autor

Kedziora J.

autor

Tyslerowicz P.

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