Protein kinases as targets for anti-parasitic chemotherapy

• Autorzy: Doerig C
• Języki publikacji: EN

Słowa kluczowe

EN

parasite; public health; antiparasitic chemotherapy; man; pathogen; Protozoa; chemotherapeutic agent; food production; protein kinase; domestic animal

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2003
• Tom: 08
• Numer: 2A
• Opis fizyczny: p.524-525

Twórcy

autor

Doerig C

• University of Glasgow, 56 Dumbarton Road, Glasgow G11 6NU, Scotland, U.K.

Bibliografia

• 1. http://www.who.int/tdr/index.html, http://www.malaria.org and links therein
• 2. Doerig, C., Meijer, L. and Mottram, J. Protein kinases as drug targets in parasitic protozoa. Trends. Parasitol. 18 (2002) 366-371.
• 3. Hammarton, T.C., Mottram J.C. and Doerig, C. The cell cycle of parasitic protozoa: potential for chemotherapeutic exploitation. Prog. Cell Cycle Res. 5 (2003) 91-101.
• 4. Gurnett, A.M., Liberator, P.A., Dulski, P.M., Salowe, S.P., Donald, R.G., Anderson, J.W., Wiltsie, J., Diaz, C.A., Harris, G., Chang, B., Darkin-Rattray, S.J., Nare, B., Crumley, T., Blum, P.S., Misura, A.S., Tamas, T., Sardana, M.K., Yuan, J., Biftu, T. and Schmatz, D.M. Purification and molecular characterization of cGMP-dependent protein kinase from Apicomplexan parasites. A novel chemotherapeutic target. J. Biol. Chem. 277 (2002) 15913-15922.
• 5. Knockaert, M., Gray, N., Damiens, E., Grellier, P., Grant, K., Fergusson, D., Mottram, J., Soete, M., Dubremetz, J.-F., Le Roch, K., Doerig, C., Schultz, P.G. and Meijer, L. Intracellular targets of cyclin-dependent kinase inhibitors : Identification by affinity chromatography using immobilized inhibitors. Chem. Biol. 7 (2000) 411-422.