Nowa wersja platformy, zawierająca wyłącznie zasoby pełnotekstowe, jest już dostępna.
Przejdź na https://bibliotekanauki.pl

PL EN


Preferencje help
Widoczny [Schowaj] Abstrakt
Liczba wyników
Czasopismo
2003 | 62 | 3 | 167-170
Tytuł artykułu

Localisation of NADPH-diaphorase-positive structures in the thymus of the rat, mouse and rabbit

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
Localisation of the diaphorase activity of nicotinamide adenine dinucleotide phosphate (NADPH-d), acting as a marker of nitric oxide synthesis (NOS), was studied in the thymus of the rat, mouse and rabbit. The NADPH-d-active cells observed in the rat thymus were irregular in shape with numerous projections and were located on the boundary between the cortex and the medulla. The NADPH-d-active cells in the thymus of the mouse were located predominantly in the medulla. They varied in coloration and their shape was oval, round, or irregular. NADPH-d-positive nerve fibres were located perivascularly. The rabbit thymus displayed a lightly stained cortex, whereas the medulla was seen as a rounded complex of intensively stained cells, without sharp demarcation between them. In the rat thymus, the NADPH-d-positive nerve fibres were not evident, whereas NADPH-d-positive nerve fibres were seen in the perivascular topography of the mouse and the rabbit thymus. These results suggest that NO may participate in the regulation of the thymic function in the species. In summary, the present results reveal the distribution of NADPH-diaphorase-d-positive structures in the rat, mouse and rabbit thymus.
Słowa kluczowe
Wydawca
-
Czasopismo
Rocznik
Tom
62
Numer
3
Strony
167-170
Opis fizyczny
p.167-170,fig.,ref.
Twórcy
autor
  • University of Veterinary Medicine, Komenskeho 73, 041 81 Kosice, Slovak Republic
autor
autor
autor
Bibliografia
  • 1. Aimi Y, Fujimura M, Vincent SR, Kimura H (1991) Localization of NADPH-diaphorase containing neurons in sensory ganglia of the rat. J Comp Neurol, 306: 382–392.
  • 2. Albina JR, Henry WL (1991) Suppression of lymphocyte proliferation through the nitric-oxide synthesizing pathway. J Surg Res, 110: 327–334.
  • 3. Anderson CR (1992) NADPH-diaphorase positive neurons in the rat spinal cord include a subpopulation of autonomic preganglionic neurons. Neurosci Lett, 139: 280–284.
  • 4. Boeckxstaens GE, Pelckmans PA, Bult H, De Man JG, Herman AG, Van Maercke N (1992) The arginine-nitric oxide pathway mediates non-adrenergic non-cholinergic neurotransmission in gastrointestinal tissue. Guanidino Compounds in Biology and Medicine, Chapter 13, John Libbey Company Ltd, 89–96.
  • 5. Bredt DS, Glatt CE, Hwang P M, Fotuhi M, Dawson TM, Snyder SH (1991) Nitric oxide synthase protein and mRNA are discretely localized in neuronal populations of the mammalian CNS together with NADPH diaphorase. Neuron, 7: 615–624.
  • 6. Bulloch K, Pomerantz W (1984) Autonomic nervous system innervation of thymic-related lymphoid tissue in wildtype and nude-mice. J Comp Neurol, 228: 57–68.
  • 7. Burnett AL, Lownestein CJ, Bredt DS, Chang TS, Snyder SH (1992) Nitric oxide: a physiologic mediator of penile erection. Science, 257: 401–403.
  • 8. Dawson TM, Bredt DS, Fotuhi M, Hwang PM, Snyder SH (1991) Oxide synthase and neuronal NADPH-diaphorase are identical in bram an peripheral tissues. Proc Natl Acad Sci, USA 88: 7797–7801.
  • 9. Dorko F, Gomboš A, Kocišová M, Gregor A (1993) Innervation of the thymus in the prenatal period. Funct Develop Morphol, 3; 1: 32–33.
  • 10. Dorko F, Kocišová M, Gregor A, Dorko E (1996) The thymus — primary lymphatic organ. Slov Lek, 7: 15–17.
  • 11. Dorko F, Kocišová M, Gregor A, Dorko E (1998) Localization of NADPH-d positive cells in thymuses of pheasant and mice. Brat Lek Listy, 99, 2: 104–107.
  • 12. Dorko F, Kocišová M, Sirotáková M, Schmidtová K, Lovásová K, Dorko E (2000) The localization of NADPH-d positive cells and autonomic innervation of the rat thymus. Pakistan J Biol Sci, 5: 759–762.
  • 13. Downing JEG (1994) Multiple nitric oxide synthase systems in adult rat thymus revealed using NADPH-diaphorase histochemistry. Immunology, 82: 659–664.
  • 14. Grozdanovic Z, Baumgarten HG, Bruning G (1992) Histochemistry of NADPH-diaphorae, a marker for neuronal nitric oxide synthase, in the peripheral autonomic nervous system of the mouse. Neuroscience, 48: 225–235.
  • 15. Gulati P, Chan AS, Leong SK (1993) NADPH-diaphorase positive cells in the chick and rat thymus. Thymus, 22: 117–124.
  • 16. Hope BT, Michael GJ, Knigge KM, Vincent SR (1991) Neuronal NADPH-diaphorase is a nitric oxide synthase. Proc Natl Acad Sci USA, 88: 2811–2814.
  • 17. Kiechle FL, Maliski T (1993) Nitric oxide biochemistry, pathophysiology, and detection. Am J Clin Pathol 100: 567–573.
  • 18. Kocišová M, Gomboš A, Gregor A, Bánkovská E, Dorko F (1992) Innervation of the rat thymus. Folia Fac Med Univ Śafarik Cass XLIX: 53–58.
  • 19. Mizukawa K (1990) Reduced nicotinamide adenine dinucleotide phosphate-diaphorase histochemistry: Light and electron microscopic investigations. In: Methods in Neuroscience. 3 Ed. Academic Press, Inc. 457–472.
  • 20. Shimosegawa T, Takashi A, Akihiko S, Reishi A, Yoshifumi K, Masaru K, Takayoshi T (1993) NADPH-diaphorase activity in neurons of the mammalian pancreas: Coexpression with vasoactive intestinal polypeptide. Gastroenterology, 105: 999–1008.
  • 21. Scherer-Singler U, Vincent SR, Kimura H, McGeer EG (1983) Demonstration of a unique population of neurons with NADPH-diaphorase histochemistry. J Neurosci Methods, 8: 229–234.
  • 22. Schmidt HHHW, Gague GD, Nakane M, Pollock JS, Miller MF, Murad F (1992) Mapping of neural NO synthase in the rat suggests frequent localization with NADPH-diaphorase but not soluble guanylyl cyclase and novel paraneural functions for nitrinergic signal transduction. J Histochem Cytochem 40: 1439–1456.
  • 23. Singh U (1984) Sympathetic innervation of fetal mouse thymus. Eur J Immunol, 14: 757–759.
  • 24. Sirotáková M, Stopek D, Kocišová M, Dorko F (1997) Development of adrenergic and ACHE-positive innervation in bursa cloacalis (Fabricii) in pheasants: a histochemical study. Folia Fac Med Univ Śafarik Cass, 54: 71–81.
  • 25. Syed MA, Leong SK, Chan AS (1994) Localization of NADPH-diaphorase reactivity in the chick and mouse thyroid gland. Thyroid, 4: 475–478.
  • 26. Valtschanoff JG, Weinberg RJ, Rustioni A (1992) NADPH-diaphorase in the spinal cord of rats. J Comp Neurol 321: 209–222.
  • 27. Vanderwinden JM, Mailleuz P, Schiffmann SN, Vanderhaeghen JJ, De Laet MH (1992) Nitric oxide synthase activity in infantile hypertropic pyloric stenosis. N Engl J Med 327: 511–515.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-article-d4b0149f-dbf1-4fb1-9ebe-5b5185faf383
JavaScript jest wyłączony w Twojej przeglądarce internetowej. Włącz go, a następnie odśwież stronę, aby móc w pełni z niej korzystać.