Swinie jako rezerwuar wirusow grypy w aspekcie epidemii wywolanej nowym szczepem A H1N1

• Autorzy: Markowska-Daniel I

Warianty tytułu

EN

Pigs as a reservoir of influenza viruses in aspect of epidemic caused by A H1N1 strain

• Języki publikacji: PL

Abstrakty

EN

Human and animals influenza is caused by the virus possessing 8 RNA segments in the genome. The segmented nature is critical structural feature that allows influenza viruses to undergo genetic reassortment. Pigs are important reservoir of influenza viruses because they express two types of receptors in the trachea which can bind swine, human and avian influenza viruses during infection. Therefore reassortation of viruses’ segments from different origin and subtypes can occur and facilitate in this way the generation of the strains with pandemic potential. Pigs can infect human with influenza virus directly which was several times confirmed. However the monitoring of pig care takers health indicate that it happened occasionally. In April 2009 the first cases of influenza, caused by the new strain of influenza type A H1N1, possessing genes of swine origin of unknown combination, occurred in North America. Within few days influenza spread and over 1000 people in 21 countries developed the illness, including 27 deaths. New A H1N1 strain possesses pandemic potency and is transmitted between humans only. Up to now none of the cases reported worldwide have had any direct contact with pigs. More over infected person introduced the mutant into the pig herd which may increase the risk of further reassortation. Data concerning the epidemic of A H1N1 strain are presented in this paper.

Słowa kluczowe

PL

czynniki chorobotworcze; wirusy; wirus influenzy; wirus influenzy swin; wirus A H1N1; zmiennosc genetyczna; transmisja wirusow miedzygatunkowa; rezerwuary zarazka; trzoda chlewna; epidemie

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2009
• Tom: 65
• Numer: 06
• Strony: 363-368
• Opis fizyczny: s.363-368,rys.,bibliogr.

Twórcy

autor

Markowska-Daniel I

• Panstwowy Instytut Weterynaryjny - Panstwowy Instytut Badawczy, Al.Partyzantow 57, 24-100 Pulawy

Bibliografia

• 1. Alexander D. J., Brown I. H.: Recent zoonoses caused by influenza A viruses. Rev. Sci. Tech. 2000, 19, 197-225.
• 2. Brown I. H.: The epidemiology and evolution of influenza viruses in pigs. Vet. Microbiol. 2000, 74, 29-46.
• 3. Castrucci M. R., Donatelli I., Sidoli L., Barigazzi G., Kawaoka Y., Webster R. G.: Genetic reassortment between avian and human influenza A viruses in Italian pigs. Virol. 1993, 193, 503-506.
• 4. Cox N. J., Bender C. A.: The molecular epidemiology of influenza viruses. Virol. 1995, 6, 359-370.
• 5. Gray G. C., McCarthy T., Capuano A. W., Setterquist S. F., Olsen C. W., Alavanja M. C.: Swine workers and swine influenza virus infections. Emerg. Infect. Dis. 2007, 13, 1871-1878.
• 6. Gregory V., Lim W., Cameron K., Bennett M., Marozin S., Klimov A., Hall H., Cox N., Hay A., Lin Y. P.: Infection of a child in Hong Kong by an influenza A H3N2 virus closely related to viruses circulating in European pigs. J. Gen. Virol. 2001, 82, 1397-1406.
• 7. Landolt G. A., Karasin A. I., Philips L., Olsen C. W.: Comparison of the pathogenesis of two genetically different H3N2 influenza A viruses in pigs. J. Clin. Microbiol. 2003, 41, 1936-1941.
• 8. Markowska-Daniel I., Kowalczyk A.: Wpływ zmienności na międzygatunkową transmisję zakażeń wirusem grypy. Medycyna Wet. 2006, 9, 981-986.
• 9. Myers K. P., Olsen C. W., Gray G. C.: Cases of swine influenza in humans: a review of the literature. Clin. Infect. Dis. 2007, 44, 1084-1088.
• 10. Newman A. P., Reisdorf E., Beinemann J., Uyeki T. M., Balish A., Shu B.: Human case of swine influenza A (H1N1) triple reassortant virus infection, Wisconsin. Emerg. Infect. Dis. 2008, 14, 1470-1472.
• 11. Olsen C. W.: The emergence of novel swine influenza viruses in North America. Virus Res. 2002, 85, 199-210.
• 12. Olsen C. W., Brammer L., Easterday B. C., Arden N., Belay E., Baker I., Cox N. J.: Serological evidence of H1 swine influenza virus infection in swine farm residents and employees. Emerg. Infect. Dis. 2002, 8, 814-819.
• 13. Olsen C. W., Brown I. H., Easterday B., Van Reeth K.: Swine influenza, [w:] Straw B. E., Zimmerman J. J., D'Allaire S., Taylor D. J.: Diseases of Swine, Blackwell Publishing, Ames, Iowa, USA 2006, s. 469-482.
• 14. Reeth Van K.: Avian and swine influenza viruses: our current understanding of the zoonotic risk. Vet. Res. 2007, 38, 243-260.
• 15. Reeth Van K., Nicoll A.: A human case of swine influenza virus infection in Europe - implications for human health and research. Euro Surveill. 2009, 14, 1-3.
• 16. Robinson J. L., Lee B. E., Patel J., Bastien N., Grimsrud K., Seal R. F., King R., Marshall F., Li Y.: Swine influenza (H3N2) infection in a child and possible community transmission. Canadian Emerg. Infect. Dis. 2007, 13, 1865-1870.
• 17. Schweiger B., Zadow I., Heckler R.: Antigenic drift and variability of influenza viruses. Med. Microbiol. Immunol. 2002, 191, 133-138.
• 18. Suzuki Y.: Sialobiology of influenza: molecular mechanism of host range variation of influenza viruses. Biol. Pharm. Bull. 2005, 28, 399-408.
• 19. Wells D. L., Hopfensperger D. J., Arden N. H., Harmon M. W., Davis J. P., Tipple M. A., Schonberger L. B.: Swine influenza virus infections. Transmission from ill pigs to humans at a Wisconsin agricultural fair and subsequent probable person-to-person transmission. JAMA 1991, 265, 478-481.
• 20. Zell R., Bergmann S., Krumbholz A., Wutzler P., Dürrwald R.: Ongoing evolution of swine influenza viruses: a novel reassortant. Arch. Virol. 2008, 153, 2085-2092.
• 21. Zhou N. N., Senne D. A., Landgraf J. S., Swenson S. L, Erickson G., Rossow K., Liu L., Yoon K. J., Kraus S., Webster R. G.: Genetic reassortment of avian, swine, and human influenza A viruses in American pigs. J. Virol. 1999, 73, 8851-8856.