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2003 | 21 | 3 |
Tytuł artykułu

Growth rate and carcass quality in pigs as related to genotype at loci POU1F1-RsaI [Pit-RsaI] and GHRH-AluI

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The aim of the study was to determine the effect of pituitary transcription factor 1 (POU1F1, Pit1) and the polymorphism of growth hormone releasing hormone (GHRH) genes on selected pig performance traits. The animals used were the progeny of Polish Landrace × Polish Large White crossbred sows and Polish Landrace, Polish Large White, Duroc or Pietrain boars. Eighteen perfor-mance traits were recorded. The POU1F1 genotype was found to have a significant effect on mean daily live weight gain (g), ham-covering fat (kg), fat thickness over loin (cm), meat content of carcass (%) and meat content of (%), while the GHRH/AluI genotype was significantly associated with fat thickness over shoulder (cm) and meat content of carcass (%). The results presented show that the region of chromosome 13, covering the POU1F1-encoding gene, may contain quantitative traits loci (QTLs) for growth rate and carcass traits. The study supplied new information on the relation between the polymorphism of GHRH-encoding gene and pig performance.
PL
Przedmiotem badań było określenie zależności między polimorfizmem genów POU1F1 (przysadkowego czynnika transkrypcyjnego) i GHRH (somatoliberyny) a cechami użytkowymi świń. Materiałem były zwierzęta pochodzące z krzyżowania knurów czystych ras (pbz, wbp, Duroc, Pietrain) z lochami mieszańcowymi (wbp × pbz). Analizą objęto 18 cech tempa wzrostu i jakości tuszy 322 zwierząt. Istotne różnice między analizowanymi genotypami POUF1/RsaI w odniesieniu do badanych cech uzyskano dla procentu mięsa w tuszy, procentu mięsa w szynce, masy słoniny okrywającej szynkę ze skórą, grubości słoniny nad okiem polędwicy oraz średniego dziennego przyrostu.
Wydawca
-
Rocznik
Tom
21
Numer
3
Opis fizyczny
p.159-166
Twórcy
autor
  • Polish Academy of Sciences, Jastrzebiec, 05-552 Wolka Kosowska, Poland
autor
Bibliografia
  • 1. ANDERSSON L., HALEY C.S., ELLEGREN H., KNOTT S.A., JOHANSSON M., ANDERSSON K., ANDERSSON-EKLUND L., EDFORS-LILJA I., FREDHOLM M., HANSSON I., HAKANSSON J., LUNDSTROM K., 1994 – Genetic mapping of quantitative trait loci for growth and fatness in pigs. Science 263, 1771-1774.
  • 2. ARCHIBALD A.L., HALEY C.S., BROWN J.F., COUPERWHITE S., MCQUEEN H.A., NICHOLSON D., COPPIETERS W., VAN DE WEGE A., STRATIL A., WINTERO A.K., FREDHOLM M.,LARSEN N.J., NIELSEN V. H., MILAN D., WOLOSZYN N., ROBIC A., DALENS M., RIQUET J., GELLIN J., CARITEZ J.-C., BURGAUD G., OLLIVIER L., BIDANEL J. -P., VAIMAN M.,RENARD C., GELDERMANN H., DAVOLI R., RUYTER D., VERSTEGE E.J.M., GROENEN M.A.M., DAVIES W., HOYHEIM B., KEISERUD A., ANDERSSON L., ELLEGREN H., JOHANSSON M., MARKLUND L., MILLER J.R., ANDERSON DEAR D.V., SIGNER E., JEFFREYS A.J.,MORAN, LE TISSIER P., MULADNO, ROTHSCHILD M.F., TUGGLE C.K., VASKE D., HELM J., LIU H.-C., RAHMAN A., YU T.-P., LARSON R.G., SCHMITZ C.B., 1995 – The PigMap consortium linkage map of the pig. Mammalian Genome 6, 157-175.
  • 3. BASKIN L.C, POMP D., 1997 – Restriction fragment length polymorphism in amplification products of the porcine growth hormone releasing hormone gene. Journal of Animal Science 75, 22-85.
  • 4. BIDANEL J.P., ROTHSCHILD M., 2002 – Current status of quantitative trait locus mapping in pigs.Pigs News and Information 23, 40-53.
  • 5. BRUNSCH C., STERNSTEIN I., REINECKE P., BIENIEK J., 2002 – Analysis of associations of POU1F1 genotypes with growth, meat quality and carcass composition traits in pigs. Journal of Applied Genetics 43(1), 85-91.
  • 6. DRAGHIA-AKLI R., FIOROTTO M.L., HILL L.A., MALONE P.B., DEAVER D.R., SCHWARTZ R.J., 1999 – Myogenic expression of an injectable protease-resistant growth hormone-releasing hormone augments long-term growth in pigs. Nature Biotechnology 17, 1179-1183.
  • 7. INGRAHAM H.A., FLYNN S.E., VOSS J.W., ALBERT V.R., KAPILOFF M.S., WILSON L.,ROSENFELD M.G., 1990 – The POU-specific domain of Pit-1 is essential for sequence-specific,high affinity DNA binding and DNA-dependent Pit-1-Pit-1 interactions. Cell 61, 1021-1033.
  • 8. KURYŁ J., PIERZCHAŁA M., 2001 – Association of POUF1/Rsa1 genotypes with carcass traits in pigs. Journal of Applied Genetics 42, 309-316
  • 9. KURYŁ J., KAPELANSKI W., PIERZCHAŁA M., CIESLAK D., 2000 – Ocena wpływu polimorfizmu genu GHRH (hormon uwalniający hormon wzrostu – somatoliberyna) na zawartość mięsa w tuszy świń (Evaluation of GHRH gene polymorphism effect on meat deposition in carcass of pig).In Polish with English summary. Zeszyty Naukowe Przeglądu Hodowlanego 48, 391.
  • 10. MOSER G., MULLER E., BEECKMANN P., YUE G., GELDERMANN H., 1998 – Mapping of QTLs in F2 generations of Wild Boar, Pietrain and Meishan pigs. Proceedings of the 6th World Congress on Genetics Applied to Livestock Production, Armidale, Australia, 26, 478-481.
  • 11. RADOVICK S., NATIONS M., DU Y., BERG L.A., WEINTRAUB B.D., WONDISFORD F.E.,1992 – A mutation in the POU-homeodomain of POU1F1 responsible for combined pituitary hormone deficiency. Science 257, 1115-1118.
  • 12. SALVATORI R., FAN X., MULLIS P.E., HAILE A., LEVINE M.A., 2002 – Decreased expression of the GHRH receptor gene due to a mutation in a Pit-1 binding site. Molecular Endocrinology 16,450-8.
  • 13. SHI X.W., TUGGLE C.K., 2001 – Rapid communication: genetic linkage and physical mapping of the porcine phospholipid transfer protein (PLTP) gene. Journal of Animal Science 79, 1633-4.
  • 14. STANECKOVA K., VASICEK D., PESTKOVICOVA D., BULLA J., KUBEK A., 1999 – Effect of genetic variability of porcine pituitary-specific transcription factor (PIT-1) on carcass traits in pigs.Animal Genetics 30, 313-315.
  • 15. STEINFELDER H.J., HAUSER P., NAKAYAMA Y., RADOVICK S., MCCLASKEY J.H., TAYLOR T., WEINTRAUB B.D., WONDISFORD F.E., 1991 – Thyrotropin-releasing hormone regulation of human TSHb expression: role of a pituitary specific transcription factor (PIT1/GHF-1) and potential interaction with a thyroid hormone-inhibitory element. Proceedings of the National Academy Sciences, USA 88, 3130- 3134.
  • 16. SUN H.S., ANDERSON L.L., YU T.P., KIM K.S., KLINDT J., TUGGLE C.K., 2002 – Neonatal Meishan pigs show POU1F1 genotype effects on plasma GH and PRL concentration. Animal Reproduction Science 15, 223-37
  • 17. WILKIE P.J., PASZEK A.A., FLICKINGER G.H., ROHRER G.A., ALEXANDER L.J., BEATTIE C.W., 1996 – Scan of 8 porcine chromosome for growth, carcass and reproductive traits reveals two likely quantitative trait loci. Animal Genetics 27, 117-118.
  • 18. YU T.-P., SCHMITZ C.B., ROTHSCHILD M.F., TUGGLE C.K., 1994 – Expression pattern, genomic cloning and RFLP analyses of the swine POU1F1 gene. Animal Genetics 25, 229-233.
  • 19. YU T.-P., TUGGLE C.K., SCHMITZ C.B., ROTHSCHILD M.F., 1995 – Association of POU1F1 polymorphisms with growth and carcass traits m pigs. Journal of Animal Science 73, 1282-1288.
  • 20. YU T.-P., WANG L., TUGGLE C.K., ROTHSCHILD M. F., 1999 – Mapping genes for fatness and growth on pig chromosome 13: a search for the region close to the pig PIT1 gene. Journal of Animal Breeding and Genetics 116, 269-280
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-article-b49cb624-7d87-4013-b829-5fbbfb04c851
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