Warianty tytułu
Języki publikacji
Abstrakty
Loss of homeostasis is a hallmark of malignant tumorigenesis and autoimmune diseases. Recent studies have implicated apoptotic cell death pathways in initiating and propagating autoimmune diseases in susceptible individuals. During malignancy, however, there is an accumulation of cells resistant to apoptosis. Intriguingly, some patients with malignant tumors develop symptoms that cannot be explained solely on the basis of the effects produced by either the primary tumor or its metastases. The mechanisms responsible for these complex symptoms, known as paraneoplastic autoimmunity, remain the focus of investigation.
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Opis fizyczny
p.61-64,fig.,ref.
Twórcy
autor
- Centre Viggo Petersen, Hopital Lariboisiere, 2, rue Ambroise Pare University Paris 7, F-75475 Paris Cedex 10, France
Bibliografia
- Cho-Chung YS (2006) Autoantibody biomarkers in the detection of cancer. Biochim Biophys Acta 1762: 587-591.
- Demaison C, Chastagner P, Theze J, Zouali M (1994) Somatic diversification in the heavy chain variable region genes expressed by human autoantibodies bearing a lupus-associated nephritogenic anti-DNA idiotype. Proc Natl Acad Sci USA 91: 514-518.
- Gouin-Thibault I, Achkar A, Samama MM (2001) The thrombophilic state in cancer patients. Acta Haematol 106: 33-42.
- Gronbaek K, Straten PT, Ralfkiaer E, Ahrenkiel V, Andersen MK, Hansen NE, Zeuthen J, Hou-Jensen K, Gul- dberg P (1998) Somatic Fas mutations in non-Hodgkin’s lymphoma: association with extranodal disease and autoimmunity. Blood 92: 3018-3024.
- Levinson AI, Zheng Y, Gaulton G, Moore J, Pletcher CH, Song D, Wheatley LM (2003) A new model linking in- trathymic acetylcholine receptor expression and the pathogenesis of myasthenia gravis. Ann NY Acad Sci 998: 257-265.
- Radic MZ, Zouali M (1996) Receptor editing, immune diversification, and self-tolerance. Immunity 5: 505-511.
- Ramos-Casals M, Trejo O, Garcia-Carrasco M, Cervera R, De La Red G, Gil V, Lopez-Guillermo A, Ingelmo M, Font J (2004) Triple association between hepatitis C virus infection, systemic autoimmune diseases, and B cell lymphoma. J Rheumatol 31: 495-499.
- Sakaguchi S (2000) Regulatory T cells: key controllers of immunologic self-tolerance. Cell 101: 455-458.
- Schwartz RH (1989) Acquisition of immunologic self-tolerance. Cell 57: 1073-1081.
- Viau M, Zouali M (2005) B-lymphocytes, innate immunity, and autoimmunity. Clin Immunol 114: 17-26.
- Zhang B, Zheng R, Wang J, Bu D, Zhu X (2006) Epitopes in the linker subdomain region of envoplakin recognized by autoantibodies in paraneoplastic pemphigus patients. J Invest Dermatol 126: 832-840.
- Zouali M (2002) B cell diversity and longevity in systemic autoimmunity. Mol Immunol 38: 895-901.
- Zouali M (2005) Taming Lupus. Sei Am 292: 70-77.
- Zouali M, Fine JM, Eyquem A (1984) A human monoclonal IgGl with anti-idiotypic activity against anti-human thy- roglobulin autoantibody. J Immunol 133: 190-194.
- Zouali M, Fine JM, Eyquem A (1984) Anti-DNA autoantibody activity and idiotypic relationships of human monoclonal proteins. Eur J Immunol 14: 1085-1089.
- Zouali M, Sarmay G (2004) B lymphocyte signaling pathways in systemic autoimmunity: implications for pathogenesis and treatment. Arthritis Rheum 50: 2730-2741.
Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
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