The outcome of autologous chondrocyte transplantation treatment of cartilage lesions in the knee

• Autorzy: Drobnic M , Kregar-Velikonja N. , Radosavljevic D. , Gorensek M. , Koritnik B. , Malicev E. , Wozniak G. , Jeras M. , Knezevic M.
• Języki publikacji: EN

Abstrakty

EN

Recent results of the clinical outcome of autologous chondrocyte transplantation (ACT) treatment in a group of 28 patients with focal femoral condyle cartilage lesions revealed a correlation trend with the quality of the in vitro cell culture matrix-protein synthesis. No impact of the patients' age and chondrocyte cryopreservation prior to implantation was observed. Further studies are needed to confirm the preliminary results.

Słowa kluczowe

EN

patient; knee; surgery; cartilage; chondrocyte; age; matrix-protein synthesis; transplantation

• Wydawca: -
• Czasopismo: Cellular and Molecular Biology Letters
• Rocznik: 2002
• Tom: 07
• Numer: 2
• Opis fizyczny: p.361-363,fig.

Twórcy

autor

Drobnic M

• Clinical Centre, Zaloska 9, SI-1000 Ljubljana, Slovenia

autor

Kregar-Velikonja N.

autor

Radosavljevic D.

autor

Gorensek M.

autor

Koritnik B.

autor

Malicev E.

autor

Wozniak G.

autor

Jeras M.

autor

Knezevic M.

Bibliografia

• 1. Peterson, L., Minas, T., Brittberg, M., Nilsson, A., Sjogren-Jansson, E. and Lindhal, A. Two- to 9-year outcome after autologous chondrocyte transplantation of the knee. Clin. Ortop. 374 (2000) 212-234.
• 2. Drobnič, M., Radosavljevič, D., Koritnik, B., Gorenšek, M., Kregar- Velikonja, N., Jeras, M. and Knežević, M. Five years of autologous chondrocyte transplantation (ACT) for the knee cartilage lesions. In: Cartilage Weekend. The 2nd symposium of recent advances in cartilage repair and tissue engineering. (Koritnik, B., Radosavljevič, D., Gorenšek, M. Eds.) Ljubljana: Orthopaedic Clinic, Clinical Centre. (2001) 48.
• 3. Kregar Velikonja, N., Wozniak, G., Maličev, E., Jeras, M. and Knežević, M. Protein synthesis of human articular chondrocytes cultured in vitro for autologous transplantation. Pflugers. Arch. Eur. J. Physiol. 442 (2001) Suppl 1 R169-R170.
• 4. ICRS Comitee. The cartilage standard evaluation form/knee. ICRS Newsletter 1 (1998) 5-8.