Experimental transmission of Cryptosporidium parvum isolates from wild rodents and calves to laboratory bred common voles [Microtus arvalis]

• Autorzy: Donskow K , Bajer A. , Bednarska M. , Sinski E.
• Języki publikacji: EN

Abstrakty

EN

The oocysts of Cryptosporidium parvum isolated from Microtus arvalis, Clethrionomys glareolus and calves were used in laboratory experiments carried out on 35 M. arvalis. Oocysts were detected in 43% of 14 voles infected with C. parvum derived from calves and in 54% of 13 voles infected with C. parvum isolates from C. glareolus. All voles inoculated with oocysts from M. arvalis (MA-voles) developed infection. There were observed differences in courses of infection between the three groups of voles with MA-voles demonstrating the most typical curve with an acute phase of infection in the first 4 weeks and a 2-week- long phase of self-curing. The infections with 'heterologous' C. parvum isolates (C. glareolus and calf isolates) transformed into chronic infections with lower oocyst productions. A strong host age effect was observed on prevalence of C. parvum among voles of different ages. Eight-month-old voles did not become infected and in older animals the infections were milder. The successful cross-transmission of two C. parvum isolates to M. arvalis suggests that this species should be considered as reservoir host for this important parasite of humans and animals.

Słowa kluczowe

EN

Cryptosporidium parvum; parasite; calf; isolate; infectivity; mammal; man; experimental transmission; Microtus arvalis; wild rodent; rodent; oocyst

• Wydawca: -
• Czasopismo: Acta Parasitologica
• Rocznik: 2005
• Tom: 50
• Numer: 1
• Opis fizyczny: p.19-24,fig.,ref.

Twórcy

autor

Donskow K

• Warsaw University, 1 Miecznikowa Street, 02-096 Warsaw, Poland

autor

Bajer A.

autor

Bednarska M.

autor

Sinski E.

Bibliografia

• Bajer A., Bednarska M., Pawełczyk A., Behnke J.M., Gilbert F.S., Siński E. 2002. Prevalence and abundance of Cryptosporidium parvum and Giardia spp. in wild rural rodents from Mazury Lake District region of Poland. Parasitology, 125, 21-34.
• Bajer A., Bednarska M., Siński E. 2004. Molekularne badania inwazji Cryptosporidium spp. Medycyna Weterynaryjna, in press.
• Bajer A., Behnke J.M., Bednarska M., Kanicka M., Siński E. 2000. The common vole (Microtus arvalis) as a competent host for Cryptosporidium parvum. Acta Parasitologica, 45, 178.
• Bajer A., Caccio S., Bednarska M., Behnke J.M., Pieniążek N.J, Siński E. 2003. Preliminary molecular characterization of Cryptosporidium parvum isolates of wildlife rodents from Poland. Journal of Parasitology, 89, 1053-1055.
• Bednarska M., Bajer A., Kuliś K., Siński E. 2003. Biological characterization of Cryptosporidium parvum isolates of wildlife rodents in Poland. Annals of Agricultural and Environmental Medicine, 10, 163-169.
• Bednarska M., Bajer A., Siński E. 1998. Calves as a potential reservoir of Cryptosporidium parvum and Giardia sp. Annals of Agricultural and Environmental Medicine, 5, 135-138.
• Caccio S., Pinter E., Fantini R., Mezzaroma I., Pozio E. 2002. Human infection with Cryptosporidium felis: case report and literature review. Emerging Infectious Diseases, 8, 85-86.
• Chalmers R.M., Sturdee A.P., Bull S.A., Miller A. 1995. Rodent reservoirs of Cryptosporidium. Royal Society of Chemistry Special Publication, 168, 51-66.
• Chalmers R.M., Sturdee A.P., Bull S.A., Miller A., Wright S.E. 1997. The prevalence of Cryptosporidium parvum and C. muris in Mus domesticus, Apodemus sylvaticus and Clethrionomys glareolus in agricultural system. Parasitology Research, 83, 478-482.
• Fayer R., Trout J.M., Jenkins M.C. 1998. Infectivity of Cryptosporidium parvum oocysts stored in water at environmental temperatures. Journal of Parasitology, 84, 1165-1169.
• Garcia L.S., Bruckener D.A. 1988. Macroscopic and microscopic examination of faecal specimens. In: Diagnostic medical parasitology (Eds. L.S. Garcia and D.A. Bruckener). Elsevier Science Publishing, New York, 377-391.
• Klesius P.H., Haynes T.B., Malo L.K. 1986. Infectivity of Cryptosporidium sp. isolated from wild mice for calves and mice. Journal of the American Veterinary Medical Association, 189, 192-193.
• Korich D.G., Marshall M.M., Smith H.V., O'Grady J., Bukhari Z., Fricker C.R., Rosen J.P., Clancy J.L. 2000. Inter-laboratory comparison of the CD-1 neonatal mouse logistic dose-response model for Ciyptosporidium parvum oocysts. Journal of Eukaryotic Microbiology, 47, 294-298.
• Koudela B., Modry D., Vitovec J. 1998. Infectivity of Cryptosporidium muris isolated from cattle. Veterinary Parasitology, 76, 181-188.
• Lindsay D.S., Upton S.J., Owens D.S., Morgan U.M., Mead J.R., Blagburn B.L. 2000. Cryptosporidium andersoni n. sp. (Apicomplexa: Cryptosporiidae) from cattle, Bos taurus. Journal of Eukaryotic Microbiology, 47, 91-95.
• Mallon M., Macleod A., Wastling J., Smith H., Reilly B., Tait A. 2003. Population structures and the role of genetic exchange in the zoonotic pathogen Cryptosporidium parvum. Journal of Molecular Evolution, 56, 407-417.
• Matsui T., Fujino T., Kajiama J., Tsuji M. 2000. Infectivity to experimental rodents of Cryptosporidium parvum oocysts from Siberian chipmunks (Tamias sibiricus) originated in the People's Republic of China. Journal of Veterinary Medical Science, 62, 487-489.
• Morgan U.M., Sturdee A.P., Singleton G., Gomez M.S., Gracenea M., Torres J., Hamilton S. G., Woodside D.P., Thompson R.C. 1999. The Cryptosporidium "mouse" genotype is conserved across geographic areas. Journal of Clinical Microbiology, 37, 1302-1305.
• Morgan U.M., Weber R., Xiao L., Sulaiman I., Thompson R.C., Ndiritu W., Lai A., Moore A., Deplazes P. 2000. Molecular characterisation of Cryptosporidium isolates obtained from human immunodeficiency virus-infected individuals living in Switzerland, Kenya, and the United States. Journal of Clinical Microbiology, 38, 1180-1183.
• Morgan-Ryan U.M., Fall A., Ward L.A., Hijjawi N., Sulaiman I., Fayer R., Thompson R.C., Olson M., Lal A., Xiao L. 2002. Cryptosporidium hominis n. sp. (Apicomplexa: Cryptosporidiidae) from Homo sapiens. Journal of Eukaryotic Microbiology, 49, 433-440.
• Noordeen F., Horadagoda N.U., Faizal A.C., Rajpakse R.P., Razak M.A., Arulkanthan A. 2002. Infectivity of Cryptosporidium parvum isolated from asymptomatic adult goats to mice and goat kids. Veterinary Parasitology, 103, 217-225.
• O'Donoghue P.J. 1995. Cryptosporidium and cryptosporidiosis in man and animals. International Journalfor Parasitology, 25, 139-195.
• Quy R.J., Cowan D.P., Haynes P.J., Sturdee A.P., Chalmers R.M., Bodley-Tickell A.T., Bull S.A. 1999. The Norway rat as a reservoir host of Cryptosporidium parvum. Journal of Wildlife Diseases, 35, 660-670.
• Rasmussen K.R., Healey M.C. 1992. Experimental Cryptosporidium parvum infections in immunosuppressed adult mice. Infection and Immunity, 60, 1648-1652.
• Sherwood D., Angus K.W., Snodgras D.R., Tzipori S. 1982. Experimental cryptosporidiosis in laboratory mice. American Society for Microbiology, 38, 471-475.
• Siński E., Hlebowicz E., Bednarska M. 1993. Occurrence of Cryptosporidium parvum infection in wild small mammals in District of Mazury Lakes (Poland). Acta Parasitologica, 38, 59-61.
• Sturdee A.P., Chalmers R.M., Bull S.A. 1999. Detection of Cryptosporidium oocysts in wild mammals of mainland Britain. Veterinary Parasitology, 80, 273-280.
• Webster J.P., Macdonald D.W. 1995. Cryptosporidiosis reservoir in wild brown rats (Rattus norvegicus) in the UK. Epidemiology and Infection, 115, 207-209.
• Xiao L., Morgan U.M., Fayer R., Thompson R.C., Lal A.A. 2000. Cryptosporidium systematics and implications for public health. Parasitology Today, 16, 287-292.
• Xiao L., Fayer R., Ryan U., Upton S.J. 2004. Cryptosporidium taxonomy: recent advances and implications for public health. Clinical Microbiology Reviews, 17, 72-97.
• Yang S., Benson S.K., Du C., Healey M.C. 2000. Infection of immunosuppressed C57BL/6N adult mice with a single oocyst of Cryptosporidium parvum. Journal of Parasitology, 86, 884-887.