Immunohistochemical and electron-microscopical identification of neuroendocrine cells in the respiratory tract of rats with experimental uraemia

• Autorzy: Kasacka I , Sawicki B.
• Języki publikacji: EN

Abstrakty

EN

The aim of the present study was to characterise immunohistochemically and ultrastructurally the neuroendocrine cells in the pulmonary systems of uraemic rats. Pieces of lung and trachea were collected 1, 2 and 4 weeks after nephrectomy. Paraffin-embedded sections were stained with H+E and by silver impregnation. For the identification of neuroendocrine cells immunohistochemical reactions were performed with the use of specific antibodies against calcitonin (CT), somatostatin (SOM), synaptophysin (SYN), neuron-specific enolase (NSE) and calcitonin gene-related peptide (CGRP). For electron microscopy, ultrathin sections were used. The analysis showed an increased number of both the solitary neuroendocrine cells and of neuroepithelial bodies in uraemic rats when compared to control animals.

Słowa kluczowe

EN

calcitonin gene-related peptide; specific antibody; synaptophysin; calcitonin; uraemia; respiratory tract; neuroendocrine cell; immunohistochemistry; neuron-specific enolase; rat; somatostatin

• Wydawca: -
• Czasopismo: Folia Morphologica
• Rocznik: 2004
• Tom: 63
• Numer: 2
• Opis fizyczny: p.233-235,fig.,ref.

Twórcy

autor

Kasacka I

• Medical University, Kilinskiego 1, 15-089 Bialystok, Poland

autor

Sawicki B.

Bibliografia

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