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This review describes the structure of the adenomatous polyposis coli (APC) gene with expressed proteins and their possible tissue interactions. The functions of APC in animals and humans are discussed. The mutational spectrum with clinical impact on colon pathology and gynaecological pathology similarities are presented, along with a discussion of a highly sensitive molecular biology test.
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p.3-18,fig.
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autor
- Lublin School of Medicine, Jaczewskiego 8, 20-090 Lublin, Poland
autor
autor
autor
autor
Bibliografia
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