Skutecznosc szczepionki Alopevac przeciw grzybicy skornej

• Autorzy: Piorkowski J

Warianty tytułu

EN

Effectiveness of the Alopevac vaccine against dermatomycosis

• Języki publikacji: PL

Abstrakty

EN

Dermatophytes have the ability to invade keratinized tissue (hair, nails and skin). The invasion elicits a host response ranging from mild to severe. Local anti-dermatophyte immunity includes activation of macrophages, sensitization of T lymphocytes and the production of antibodies. Dermatophytes are eliminated from the skin by a cell-mediated immune reaction. Although antibodies play a small part in dealing with dermatophytosis, they somehow support fagocytosis and suppress adhesion of the fungus to host cells. The development of cell-mediated immunity correlated with delayed hypersensitivity is associated with clinical cure. Dermatophytoses are considered as an important epidemiological problem. Therefore, all the latest efforts to develop an effective vaccine against ringworm are significant. However, the immunology of the dermatophyte infection still remains to be comprehensively examined.

Słowa kluczowe

PL

grzybica skory; Trichophyton mentagrophytes; skutecznosc; szczepienia ochronne; profilaktyka; choroby zwierzat; szczepionki; grzybice; dermatologia weterynaryjna

• Wydawca: -
• Czasopismo: Medycyna Weterynaryjna
• Rocznik: 2006
• Tom: 62
• Numer: 06
• Strony: 674-677
• Opis fizyczny: s.674-677,rys.,tab.,bibliogr.

Twórcy

autor

Piorkowski J

• Akademia Rolnicza, ul.Gleboka 30, 20-612 Lublin

Bibliografia

• 1.Borowski J., Jakoniuk P.: Zjawiska immunologiczne w przebiegu grzybic u ludzi i zwierząt oraz zasady immunodiagnostyki, [w:] Kowszyk-Gindifer Z. (red.): Grzybice i sposoby ich zwalczania. PZWL, Warszawa 1986.
• 2.Cabanes F. J.: Animal dermatophytosis. Recent advances. Rev. Iberoam Micol. 2000, 17, 8-12.
• 3.Calderon R. A.: Immunoregulation of dermatophytosis. Critical Rev. Microbiol. 1989, 16, 339-345.
• 4.Calderon R. A., Hay R. J.: Fungicidal activity of human neutrophils and monocytes on dermatophyte fungi, Trichophyton quinckeanum and Trichophyton rubrum. Immunology 1987, 61, 289-296.
• 5.Dahl M. V.: Dermatophytes and the immune response. J. Am. Acad. Dermatol. 1994, 31, 34-38.
• 6.Dahl M. V., Carpenter R.: Polimorphonuclear leukocytes, complement, and Trichophyton rubrum. J. Invest. Dermatol. 1986, 86, 138-145.
• 7.Ferrante A., Thong Y. H.: Rapid one step procedure for purification of mononuclear and polymorphonuclear leucocytes from human blood using a modification of the Hypaque Fiol technique. J. Immunol. Methods. 1980, 34, 279-285.
• 8.Garcia-Martos P., Ruiz-Aragon J., Garcia Agudo L., Linares M.: Dermatophytoses due to Microsporum gypseum: report of eight cases and literature review. Rev. Iberoam Micol. 2004, 21, 147-149.
• 9.Green F., Balish E.: Trichophyton mentagrophytes dermatophytosis in germfree guinea pigs. J. Invest. Dermatol. 1980, 75, 476-483.
• 10.Hauck H., Skorepowa M., Simon M., Djawari D.: Intracellular killing of Trichophyton mentagrophytes microconidia by normal human polymorphonuclear leukocytes. Arch. Dermatol. Res. 1985, 278, 77-84.
• 11.Jones H. E.: Immune response and host resistance of humans to dermatophyte infection. J. Am. Acad. Dermatol. 1993, 28, 12-18.
• 12.Kostro K.: Dynamika zjawisk immunologicznych u lisów z naturalną i doświadczalną trychofitozą oraz u zwierząt immunizowanych przeciwko tej chorobie. Praca hab., Wydz. Med. Wet. AR Lublin 1998.
• 13.Kostro K.: Hypersensitivity to trichophytin in small animals experimentally infected with Trichophyton equinum. J. Med. Vet. Mycology 1989, 27, 353- -358.
• 14.Marchisio V. F., Preve L., Tullio.: Fungi responsible for skin mycoses in Turin (Italy). Mycoses 1996, 39, 141-150.
• 15.Mancianti F., Papini R.: Isolation of keratinophilic fungi from the floors of private veterinary clinics in Italy. Vet. Res. Commun. 1996, 20, 161-166.
• 16.Marina N. M., Flynn P. M., Rivera G. K., Hughes W. T.: Candida tropicalis and Candida albicans fungemia in children with leukaemia. Cancer 1991, 68, 594-600.
• 17.Meunier-Carpentier F., Kiehn T. E., Armstrong D.: Fungemia in the immunocompromised host: Changing pattems, antigenemia, high mortality. Am. J. Med. 1981, 71, 363-370.
• 18.Milan R., Alois R., Josef C., Jana B., Evzen W.: Recombinanat protein and vaccines derived from hsp60 Trichophyton mentagrophytes control the clinical course of trichophytosis in bovine species and guinea-pigs. Mycoses 2004, 47, 407-417.
• 19.Moretti A., Bancio L., Pasquali P., Fioretti D. P.: Epidemiological aspects of dermatophyte infections in horses and cattle. Zentbl. Vet. Med. 1998, 205- -208.
• 20.Moser S. A., Domer J. E.: Effect of cyclophospamide on musine candidiasis. Infect. Immunol. 1980, 27, 376-380.
• 21.Park B. H., Fikrig S. Y. M., Smithwock E. M.: Infection and nitrobluetetrazolium reduction by neutrophils. Lancet 1968, 2, 532-540.
• 22.Piórkowski J.: Ocena zmian patomorfologicznych skóry u świnek morskich w przebiegu doświadczalnej infekcji grzybem Trichophyton mentagrophytes. Annales UMCS, s. DD, vol. L.VII, 2002, 61-78.
• 23.Rajka G., Berlinn C.: On the significance of the trichophytin reactivity in atopic dermatitis. Acta Dermatovener (Stockholm) 1979, 59, 45-50.
• 24.Ray T. L.: Fungal infections in the immunocompromised host. Med. Clin. N. Am. 1980, 64, 955-961.
• 25.Siwicki A. K., Anderson D. P.: Immunostymulation in Fish: Measuring the effects of stimulants by serological and immunological methods. U.S. Fish Wildlife Service IFI Olsztyn 1993, 1, 1-2.
• 26.Szepes E., Magyarlaki M., Battyani Z., Schneider I.: Immunohistological characterization of the cellular infiltrate in dermatophytosis. Mycoses 1993, 36, 203-208.
• 27.Wawrzkiewicz J.: Trychofitoza lisów hodowlanych i jej zwalczanie. Medycyna Wet. 1999, 55, 585-592.
• 28.Wawrzkiewicz K., Chrol M.: Badania nad leczeniem i zapobieganiem trychofitozie bydła przy pomocy szczepionki Bovitrichovac. Medycyna Wet. 1977, 33, 337-343.
• 29.Wawrzkiewicz J., Wawrzkiewicz K.: Krzyżowe reakcje immunologiczne u cielat po szczepionkach przeciwko grzybicy skórnej. Medycyna Wet. 1989, 45, 605-612.
• 30.Wawrzkiewicz J., Wawrzkiewicz K., Sadzikowski Z.: Monowalentna i skojarzona szczepionka inaktywowana w profilaktyce trychofitozy lisów hodowlanych. Medycyna Wet. 1991, 47, 317-324. 31.Wołoszyn S., Andrychiewicz J., Kostro K., Grądzki: Badania nad występowaniem oraz swoistym zapobieganiem trychofitozie lisów hodowlanych. Medycyna. Wet. 1983, 39, 387-395.
• 32.Young E., Roth F. J.: Immunological cross reactivity between a glycoprotein isolated from Trichophyton mentagrophytes and human isoantigen. Am. J. Invest. Dermatol. 1979, 72, 46-52.