Czestosc wystepowania genu AAC[6']-APH[2'']Ia wsrod gronkowcow i enterokokow wysokoopornych na antybiotyki aminoglikozydowe

• Autorzy: Jarzembowski T. , Michnowska-Swincow E. , Wisniewska K.
• Języki publikacji: PL

Abstrakty

PL

Celem badań było ustalenie czy wysoka oporność na aminoglikozydy wszystkich enterokoków i gronkowców izolowanych w regionie gdańskim uwarunkowane jest obecnością genu AAC(6')-APH(2")Ia. Wśród wszystkich objętych badaniami ziarenkowców stwierdzono wysoko- oporne szczepy nie posiadające tego genu.

EN

According to new reports the AAC (6')-APH (2")Ia gene is no longer the only gene encoding resistance to gentamycin in Gram positive cocci and therefore the current method for predicting synergism aminoglycosides wit bacterial cell wall active agents in this bacteria may need revision. To further our knowledge of aminoglycoside resistance mechanism in Gram positive cocci in Gdańsk region we tested presence of AAC (6')-APH (2")Ia gene among 22 enterococcal (E. faecalis) and 41 staphylococcal (S. haemoliticus, S. aureus, S. epidermidis) gentamycin resistant isolates. Presence of AAC (6')-APH (2")Ia gene varied from 50% (n=6) in gentamycin resistant S. epidermidis, 80% (n=10) in gentamycin resistant S. haemolyticus 88% in methicylin resistant Staphylococcus aureus (MRSA) (n=25). In Enterococcus faecalis this gene was noticed only in 59 % (n=22) of gentamycin resistant isolates. These results suggest that spread of resistance gene among different species is limited and AAC (6')-APH (2")Ia mediated gentamycin resistance mechanism is more common among MRSA and Staphylococcus haemoliticus.

Słowa kluczowe

PL

gen ACC; antybiotyki aminoglikozydowe; gronkowce; szczepy bakteryjne; opornosc na antybiotyki; bakterie

• Wydawca: -
• Czasopismo: Medycyna Doświadczalna i Mikrobiologia
• Rocznik: 2003
• Tom: 55
• Numer: 4
• Strony: 309-313
• Opis fizyczny: s.309-313,tab.,bibliogr.

Twórcy

autor

Jarzembowski T.

• Akademia Medyczna, Gdansk

autor

Michnowska-Swincow E.

autor

Wisniewska K.

Bibliografia

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