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Of both drugs studied only enflurane enhanced the activities of the following enzymes: succinate dehydrogenase (SD), thiamine pyrophosphatase (TPP-ase), and acid phosphatase (AcP). The activation of metabolic processes was maximal in group 3 (after 60 min anaesthesia) and group 4 (1 hr after 60 min anaesthesia), and persisted in group 5 (24 hr after 60 min anaesthesia). Furthermore, we found an increase in the activity of lysosomal enzymes and an abnormal, diffuse Mg+2-ATP-ase reaction in the perikaryons of Purkinje cells. This indicates that these cells were damaged.
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p.25-28,fig.
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- Silesian University School of Medicine, 40-752 Katowice-Ligota, Poland
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