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2006 | 62 | 10 | 1134-1138
Tytuł artykułu

Distribution and morphology of the NOS-immunoreactive neurons in the thoracolumbar and sacral spinal cord of the pig

Warianty tytułu
Języki publikacji
EN
Abstrakty
EN
The study investigated the distribution and morphology of nitric oxide synthesis-immunoreactive neuronal cell bodies and processes in the thoracolumbar and sacral spinal cord of sexually immature gilts. Investigations revealed the following: NOS-immunoreactive fibers and singular cell bodies in regions of the dorsal horn including superficial laminae I and II and deeper laminae III and IV; prominent NOS-immunolabeled perikarya in intermediolateral nucleus of the thoracolumbar spinal segments; NOS-positive perikarya in lamina X along the thoracic, lumbar and sacral divisions of the cord; NOS-positive perikarya and fibers in the area near to the location of the intermediomedial and intermediolateral nuclei in the sacral segments of the cord. The obtained morphological results indicate that the general distribution pattern of NOS-positive neurons in the spinal cord of pigs resembles that of other species. The concentration of NO-ergic neurons in the autonomic nuclei, dorsal horn laminae I, II, III, IV and lamina X suggests a prominent role of NO-ergic neurons in visceral and sensory functions.
Wydawca
-
Rocznik
Tom
62
Numer
10
Strony
1134-1138
Opis fizyczny
p.1134-1138,fig.,ref.
Twórcy
autor
  • University of Warmia and Mazury, Oczapowskiego 13, 10-719 Olsztyn, Poland
autor
autor
autor
Bibliografia
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  • 6.Dun N. J., Dun S. L., Wu S. Y., Forstermann U., Schmidt H. H. H., Tseng L. F.: Nitric oxide synthase immunoreactivity in the rat, mouse, cat and squirrel monkey spinal cord. Neuroscience 1993, 54, 845-857.
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  • 13.Kluchova D., Schmidtova K., Rybarova S., Lovasova K., Pomfy M., Prosbova T., Vatl’ak A.: Partial colocalization of NADPH-diaphorase and acetylcholinesterase positivity in spinal cord neurons. Physiol. Res. 2000, 49, 151- -155.
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  • 15.Marsala J., Lukacova N., Sulla I., Wohlfahrt P., Marsala M.: The evidence for nitric oxide synthase immunopositivity in the monosynaptic Ia-motoneuron pathway of the dog. Exp. Neurol. 2005, 195, 161-178.
  • 16.Swindle M. M., Moody D. C., Philips L. D.: Swine as models in biomedical research. Iowa State Univ. Press. Ames. 1992, 1-312.
  • 17.Tracey W. R., Nakane M., Pollock J. S., Förstermann U.: Nitric oxide synthase in neuronal cells, macrophages and endothelium are NADPH diaphoreses, but represent only a fraction of total cellular NADPH diaphorase activity. Biochem. Biophys. Res. Commun. 1993, 195, 1035-1040.
  • 18.Valtschanoff J. G., Weinberg R. J., Rustioni A.: NADPH diaphorase in the spinal cord of rats. J. Comp. Neurol. 1992, 321, 209-222.
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Typ dokumentu
Bibliografia
Identyfikatory
Identyfikator YADDA
bwmeta1.element.agro-article-831d9c5f-a6d2-4993-b4e9-cf5f52a72742
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