Stężenia cholesterolu oraz wapnia, magnezu, cynku i miedzi w surowicy krwi w przebiegu lipemii pokarmowej u chorych z miażdżycą tętnic

• Autorzy: Iskra M. , Patelski J. , Mielcarz G. , Majewski W. , Lewandowski K.
• Języki publikacji: PL

Abstrakty

PL

W pracy oznaczono stężenia całkowite cholesterolu, Ca, Mg, Zn i Cu w surowicy krwi mężczyzn z miażdżycą tętnic w przebiegu lipemii pokarmowej. Oznaczenia prowadzono przed oraz 2, 3 i 4 godziny po posiłku tłuszczowym. Stwierdzono wzrost stężenia cholesterolu oraz obniżenie Zn cztery godziny po posiłku w grupie chorych z stężeniem wyjściowym cholesterolu ≤ 5,17 mmol/1 (I). Zmiany Zn są ujemnie skorelowane z jego stężeniem wyjściowym. Obliczono ujemne korelacje między cholesterolem a Ca (r = -0,85), Mg (r = -0,65) i Cu (r = -0,84) w grupie chorych z stężeniem cholesterolu na czczo powyżej 5,17 mmol/1 (II).

EN

The concentrations of total cholesterol, Ca, Mg, Zn and Cu in postprandial lipaemia in serum of atherosclerotic men were determined. Blood sampling were performed before and 2, 3 and 4 hours after fat-rich meal. The significant increase in serum cholesterol and the decrease in Zn concentrations four hours after meal were observed in group with fasting cholesterol below 5,17 mmol/1 (I). Changes of Zn concentrations and its 0 hour levels were found negatively correlated. Significant correlations between Ca, Mg and Cu and cholesterol (r≥-0.65) at 0 h were calculated in group with fasting cholesterol above 5,17 mmol/1 (II).

Słowa kluczowe

PL

surowica krwi; stezenie cholesterolu; miazdzyca tetnic; choroby czlowieka; wapn; cynk; magnez; miedz; cholesterol; lipemia pokarmowa

• Wydawca: -
• Czasopismo: Biuletyn Magnezologiczny
• Rocznik: 1997
• Tom: 02
• Numer: 2
• Strony: 81-87
• Opis fizyczny: s.81-87,tab.,rys.,bibliogr.

Twórcy

autor

Iskra M.

• Akademia Medyczna, 61-701 Poznan, ul.Fredry 10

autor

Patelski J.

autor

Mielcarz G.

autor

Majewski W.

autor

Lewandowski K.

Bibliografia

• Błaszczyszyn M. (1970): Dokładne i proste oznaczanie cholesterolu całkowitego w surowicy. Wiadomości Lekarskie XXIII, 16, (1413-1417)
• Brown S A, Chambless I.E., Sharrett A.R., Gotto A.M.Jr, Patsch W. (1992): Postprandial lipemia: reliability in an epidemiologie field study Am. J. Epidemiol., 136, 5 (538- 545)
• Castro G.. Fielding C.J. (1985): Effects of Postprandial Lipemia on Plasma Cholesterol Metabolism. J. Clin. Invest., 75, (874-882)
• Cohn J.S., McNamara J R., Cohn S.D., Ordovas J.M., Schaefer E.J. (1988): Postprandial plasma lipoprotein changes in human subjects of different ages. J. Lipid Res., 29, (469- 479)
• Dinsmore W.W., Callender M.E., McMaster D., Love A.H.G. (1985): The absorption of zinc from a standardized meal in alcoholics and in normal volunteers. Am. J. Clin. Nutr., 42,(688-693)
• European Atherosclerosis Society: Strategy for the prevention of coronary heart disease: a policy statement of the Eurpoean Atherosclerosis Society. (1987): Eur.Heart J. 8, (77- 88)
• Groot P.H., Scheek L.M. (1984): Effects of fat ingestion on high density lipoprotein profiles in human sera. J.Lipid Res. 23, (684-692
• Hambidge K.M., Goodal M.J., Stall C., Pritts J. (1989): Post-prandial and daily changes in plasma zinc. J. Trace Elem. Electrolytes Health Dis. 3, 1, (55-57)
• Hambidge K.M., King J.C., Kern D.L., English-Westcott J.L., Stall C. (1990): Prebreakfast plasma zinc concentrations: the effect of previous meals. J. Trace Elem. Eletrolytes Health Dis. 4, 4, (229- 231)
• Iskra M., Patelski J., Majewski W. (1993): Concentrations of Calcium, Magnesium, Zin and Copper in Relation to Free Fatty Acids and Cholesterol in Serum of Atherosclerotic Men. J. Trace Elem. Electrolytes Health Dis 7(3): 185-188
• Karpe F.; Bard, J.M.; Steiner, G; Carlson, L.A.; Fruchart, J.C.; Hamsten, A. (1993): HDLs and alimentary lipemia. Studies in me with previous myocardial infarction at a young age. Arterioscler.-Thromb. 13, 1,(11-22)
• Kasperek K, Schicha H, Hoeck A., Siller V., Feinendegen L.E. (1973): Serum zinc in dependence on time and food intake. Strahlenther, 145, (229-233)
• Markowitz M.E., Rosen J.F., Mizruchi M. (1985): Circadian variations in serum zinc (Zn) concentrations: correlation with blood ionized calcium, serum total calcium and phosphate in humans. Am. J. Clin. Nutr., 41, (689-696)
• McMaster D., McCrum E., Patterson C.C., Kerr M. (1992): Serum copper and zinc in random samples of the population of Northern Ireland. Am. J. Clin. Nutr., 56, (440- 446)
• MertzW. (1981): The Essential Trace Elements. Science, 213, (1332-1338)
• Patsch JR., Miesenbock G., Hopferwieser T., Muhlberger V., Knapp E., Dunn J.K., Gotto 4M. Jr., Patsch W. (1992): Relation of triglyceride metabolism and coronary artery disease. Studies in the postprandial state. Arterioscler.-Thromb., 12, 11, (1336-1345)
• Patelski J. (1984): Regulating effect of polyenylphosphatidylcholine on lipolytic enzyme activities of the arterial wall and serum. Proc. Int. Symp. Soya Lecithin (Ed-s: F. Paltauf, D.Lekim), Vien, 211-219
• Prasad A.S. (1992): Role of metallothionein in human health. J. Lab. Clin. Med., Sept., (357-358)
• Redgrave T.G., Carlson L.A. (1979): Changes in plasma very low density and low density lipoprotein content, composition, and size after a fatty meal in normo- and hypertriglyceridemic man. J. Lipid Res., 20, (217- 229) .
• Ryu IE., Howard G., Craven T.E., Bond M.G., Hagaman A.P., Crouse J.R. (1992): Postprandial triglyceridemia and carotid atherosclerosis in middle-aged subjects. Stroke, 23,6, (823-828)
• Sweeney M., Dinsmore W.W., McKee C.M., Love AH G. (1986): The effect of food composition on serum zinc. Acta Pharmacol. Toxicol., 59 (suppl), (170-173)
• Report of the WHO Study Group (1990): Diet, nutrition and prevention of the chronic disease. Technical Report Series No 797, Geneva
• Zhou J.R, Erdman J.W. Jr (1995): Phytic acid in health and disease. Crit. Rev. Food Sci. Nutr., 35, 6, (495-508)